Results 111 to 120 of about 527,353 (262)

IMPDH2's Central Role in Cellular Growth and Diseases: A Potential Therapeutic Target

Cell Proliferation, EarlyView.
IMPDH2 is a rate‐limiting enzyme in guanine nucleotide biosynthesis. It plays diverse roles in various physiological and pathological processes: nucleotide metabolism, inflammation, immune function, ribosomal stress. Structural or regulatory alterations in IMPDH2 are linked to significant health issues, and critical relevance in disease progression. We
Zheng Li, Yunpeng Zou, Jiayao Niu, Ying Zhang, Aohua Yang, Wenyu Lin, Jie Guo, Shuya Wang, Ronghan Liu   +8 more
wiley   +1 more source

Abnormal cerebellar connectivity and plasticity in isolated cervical dystonia.

PLoS ONE, 2019
There is increasing evidence that supports the role of the cerebellum in the pathophysiology of dystonia. We used transcranial magnetic stimulation to test the hypothesis that patients with cervical dystonia may have a disrupted cerebellar cortical ...
Paolo Porcacchia, Paloma Álvarez de Toledo, Antonio Rodríguez-Baena, Juan Francisco Martín-Rodríguez, Francisco J Palomar, Laura Vargas-González, Silvia Jesús, Giacomo Koch, Pablo Mir   +8 more
doaj   +1 more source

Pain in adults with cerebral palsy: A systematic review

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To describe the prevalence and incidence of pain, identify prognostic factors for pain, determine psychometric properties of tools to assess pain, and evaluate effectiveness of interventions for reducing pain among adults with cerebral palsy (CP).
Jennifer M. Ryan, Jessica Burke, Rachel Byrne, Emily Capellari, Adrienne Harvey, Neil E. O'Connell, Donna Omichinski, Elisabet Rodby‐Bousquet, Mark Peterson, The Adult CP Clinical Practice Guideline Working Group, Jan Willem Gorter, Ashley Harris Whaley, Christine Imms, Christina M Marciniak, Karen Brady   +14 more
wiley   +1 more source

Painful Realities: Navigating the Complexities of Head and Neck Cancer Pain

Oral Diseases, EarlyView.
ABSTRACT Background Head and neck cancer (HNC) and its treatments can cause significant pain, which can profoundly impact patients' quality of life and treatment outcomes. Understanding the full scope of HNC pain is essential for effective management and improved patient care.
Hayden F. Byrd, Zachary A. Kohutek
wiley   +1 more source

Symptomatic and functional outcome of surgical treatment of cervical dystonia [PDF]

, 1997
Joachim K. Krauss, Elizabeth G. Toups, Joseph Jankovic, Robert G. Grossman   +3 more
openalex   +1 more source

Scrub typhus‐associated movement and gait disorders: A systematic review with principal component analysis and in silico mechanistic modelling

Tropical Medicine &International Health, EarlyView.
Abstract Background Orientia tsutsugamushi, the causative agent of scrub typhus, is increasingly recognised for its neurological complications. Among these, movement and gait disorders are poorly understood. We systematically examined their clinical spectrum and explored underlying mechanisms through in‐silico protein–protein interaction modelling ...
Ritwick Mondal, Shramana Deb, Mrinmay Dhauria, Purbita Sen, Vramanti Sarkar, Shramana Sarkar, Dipanjan Chowdhury, Durjoy Lahiri, Jayanta Roy, Julián Benito‐León   +9 more
wiley   +1 more source

Treatment of cervical dystonia with botulinum toxin in a patient with myasthenia gravis [PDF]

, 1999
Márcia Rúbia Rodrigues Gonçalves, Egberto Reis Barbosa, Antônio A. Zambon, Paulo Eurípedes Marchiori   +3 more
openalex   +1 more source

Biased Visuospatial Attention in Cervical Dystonia

Journal of the International Neuropsychological Society, 2017
AbstractObjectives: There is increasing evidence of non-motor, sensory symptoms, mainly involving the spatial domain, in cervical dystonia (CD). These manifestations are likely driven by dysfunctional overactivity of the parietal cortex during the execution of a sensory task. Few studies also suggest the possibility that visuospatial attention might be
Chillemi, Gaetana, Formica, Caterina, Salatino, Adriana, Calamuneri, Alessandro, Girlanda, Paolo, Morgante, Francesca, Milardi, Demetrio, Terranova, Carmen, Cacciola, Alberto, Quartarone, Angelo, Ricci, Raffaella   +10 more
openaire   +6 more sources

Patient considerations in the treatment of cervical dystonia: focus on botulinum toxin type A

Patient Preference and Adherence, 2015
Reversa R Mills, Fernando L Pagan Department of Neurology, Movement Disorders and Neurorestoration Division, Georgetown University Hospital, Washington, DC, USA Abstract: Cervical dystonia is the most common form of focal dystonia characterized by
Mills RR, Pagan FL
doaj  

Historical aspects of studying craniocervical dystonia

Анналы клинической и экспериментальной неврологии, 2019
The study of dystonic hyperkinesias has a thousand-year-old history. Beginning with drawings and sculptures from antiquity and up to the present day, modern ideas gradually developed about the phenomenology, origin, and treatment methods of dystonia ...
Zifa G. Khayatova, Zuleykha A. Zalyalova
doaj   +1 more source