Results 111 to 120 of about 527,353 (262)
IMPDH2's Central Role in Cellular Growth and Diseases: A Potential Therapeutic Target
IMPDH2 is a rate‐limiting enzyme in guanine nucleotide biosynthesis. It plays diverse roles in various physiological and pathological processes: nucleotide metabolism, inflammation, immune function, ribosomal stress. Structural or regulatory alterations in IMPDH2 are linked to significant health issues, and critical relevance in disease progression. We
Zheng Li+8 more
wiley +1 more source
Abnormal cerebellar connectivity and plasticity in isolated cervical dystonia.
There is increasing evidence that supports the role of the cerebellum in the pathophysiology of dystonia. We used transcranial magnetic stimulation to test the hypothesis that patients with cervical dystonia may have a disrupted cerebellar cortical ...
Paolo Porcacchia+8 more
doaj +1 more source
Pain in adults with cerebral palsy: A systematic review
Abstract Aim To describe the prevalence and incidence of pain, identify prognostic factors for pain, determine psychometric properties of tools to assess pain, and evaluate effectiveness of interventions for reducing pain among adults with cerebral palsy (CP).
Jennifer M. Ryan+14 more
wiley +1 more source
Painful Realities: Navigating the Complexities of Head and Neck Cancer Pain
ABSTRACT Background Head and neck cancer (HNC) and its treatments can cause significant pain, which can profoundly impact patients' quality of life and treatment outcomes. Understanding the full scope of HNC pain is essential for effective management and improved patient care.
Hayden F. Byrd, Zachary A. Kohutek
wiley +1 more source
Symptomatic and functional outcome of surgical treatment of cervical dystonia [PDF]
Joachim K. Krauss+3 more
openalex +1 more source
Abstract Background Orientia tsutsugamushi, the causative agent of scrub typhus, is increasingly recognised for its neurological complications. Among these, movement and gait disorders are poorly understood. We systematically examined their clinical spectrum and explored underlying mechanisms through in‐silico protein–protein interaction modelling ...
Ritwick Mondal+9 more
wiley +1 more source
Treatment of cervical dystonia with botulinum toxin in a patient with myasthenia gravis [PDF]
Márcia Rúbia Rodrigues Gonçalves+3 more
openalex +1 more source
Biased Visuospatial Attention in Cervical Dystonia
AbstractObjectives: There is increasing evidence of non-motor, sensory symptoms, mainly involving the spatial domain, in cervical dystonia (CD). These manifestations are likely driven by dysfunctional overactivity of the parietal cortex during the execution of a sensory task. Few studies also suggest the possibility that visuospatial attention might be
Chillemi, Gaetana+10 more
openaire +6 more sources
Patient considerations in the treatment of cervical dystonia: focus on botulinum toxin type A
Reversa R Mills, Fernando L Pagan Department of Neurology, Movement Disorders and Neurorestoration Division, Georgetown University Hospital, Washington, DC, USA Abstract: Cervical dystonia is the most common form of focal dystonia characterized by
Mills RR, Pagan FL
doaj
Historical aspects of studying craniocervical dystonia
The study of dystonic hyperkinesias has a thousand-year-old history. Beginning with drawings and sculptures from antiquity and up to the present day, modern ideas gradually developed about the phenomenology, origin, and treatment methods of dystonia ...
Zifa G. Khayatova, Zuleykha A. Zalyalova
doaj +1 more source