Results 51 to 60 of about 31,191 (220)

Combined Transcriptomic and Proteomic Forecast Analyses for Potential Biomarkers of Smoking‐Induced Benign and Malignant Transformation of Vocal Fold Lesions

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Laryngeal dysplasia and Reinke's edema (RE) are common vocal fold lesions associated with smoking. While the former is cancer prone, most cases of the latter do not undergo malignant transformation. Therefore, we proposed identifying biomarkers of smoking‐induced benign‐malignant transformation of vocal fold lesions.
Yun‐Yi Liu, Pei‐Yun Zhuang
wiley   +1 more source

Prognostic Value of KI6 Biomarker to Predict Short Term Prognosis of Low Grade Cervical Intraepithelial Neoplasia in Human Papilloma Virus Negative and Positive Patients

Middle East Journal of Cancer, 2019
Background: Cervical cancer is the most common gynecologic cancer in developing countries. Although this malignancy is preventable, problems exist with screening this cancer. Numerous studies have researched immunohistochemistry methods, such as the KI-
Leila Mousavi Seresht, Noorieh Sharifi, Mona Najafi, Helena Azimi, Nooshin Babapour, Zohreh Yousefi, Nazanin Beheshtian, Yasaman Nikooiyan   +7 more
doaj  

DNA‐Methylation for Risk‐Stratification of Women Without a Fully Visible Transformation Zone at Colposcopy: A Cross‐Sectional Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the performance of DNA methylation markers for the detection of cervical precancer among screening‐positive older women without a fully visible transformation zone at colposcopy (TZ3). Design Cross‐sectional study. Setting Colposcopy clinics, Central Denmark Region, 2019–2021.
Karen Omann Binderup, Joachim Boers, Line Winther Gustafson, Berit Andersen, Lone Kjeld Petersen, Pinar Bor, Joost Gribnau, Wim G. V. Quint, Henk Van Den Munckhof, Mette Tranberg, Anne Hammer   +10 more
wiley   +1 more source

SOX1/PAX1 Methylation for Triage of HPV‐Positive Women in Cervical Cancer Screening: A Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To establish a better triage strategy using SOX1/PAX1 methylation detection for high‐risk HPV (hrHPV)‐positive women than cytology. Design A cohort study. Setting Population‐based cervical cancer (CC) screening cohort. Population A total of 5684 women were enrolled.
Hongyu Xie, Junyan Li, Huiru Huang, Ansong Emmanuel, Hui Wang, Weiguo Lu, Xiao Li   +6 more
wiley   +1 more source

Systemic adverse events in imiquimod use for cervical intraepithelial neoplasia – A case series

Case Reports in Women's Health, 2019
Treatment for cervical intraepithelial neoplasia (CIN) often consists of an excisional procedure. However, less invasive treatment methods have been explored, such as topical treatment with imiquimod cream.
Tirza Wouters, Natasja Hendriks, Margot Koeneman, Arnold-Jan Kruse, Anna van de Sande, Heleen J. van Beekhuizen, Kees G. Gerestein, Ruud L.M. Bekkers, Jurgen M.J. Piek   +8 more
doaj   +1 more source

HPV vaccination following cervical intraepithelial neoplasia grade 2 diagnosis and risk of progression

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
HPV vaccination in women undergoing active surveillance for CIN2 does not offer a protective effect against progression to CIN3+. Women should be informed that vaccination is not a substitute for clinical follow‐up and should be encouraged to adhere to recommended surveillance and treatment protocols Abstract Introduction Human papillomavirus (HPV ...
Dina O. Eriksen, Louise Krog, Eva B. Ostenfeld, Pernille T. Jensen, Kathrine D. Lycke, Therese K. Grønborg, Nicolas Wentzensen, Megan A. Clarke, Anne Hammer   +8 more
wiley   +1 more source

New technologies in diagnosis of preinvasive cervical lesions

Biomedical Photonics, 2015
Results of efficiency assessment of different diagnosis for preinvasive cervical lesions are represented in the article. During investigation the retrospective analysis of 353 patient histories of women with cervical intraepithelial neoplasia (primary ...
I. P. Aminodova
doaj   +3 more sources

Expression of the stem cell markers NANOG and SOX2 in the cervical squamous carcinogenesis

Radiology and Oncology
The aim of the present study was to assess a diagnostic potential of stem cell markers NANOG and SOX2 for classifying cervical squamous intraepithelial lesions (SILs)/cervical intraepithelial neoplasia (CIN).
Koren Miha, Zlajpah Margareta, Poljak Mario, Komlos Kristina Fujs, Flezar Margareta Strojan   +4 more
doaj   +1 more source

Prevention of cervical intraepithelial neoplasia and cervical cancer [PDF]

The American Journal of Clinical Nutrition, 1995
We review the current status of prevention trials in the management of cervical intraepithelial neoplasia (CIN) and cervical cancer. Two large, randomized controlled trials have shown that folic acid is inactive in reversing low to moderate grade CIN.
Meyskens, F L, Jr, Manetta, A
openaire   +5 more sources

Single‐Cell and Multiomic Analysis Reveals Neutrophil Heterogeneity and Prognostic Value in Cervical Lesions

Cancer Science, EarlyView.
This study is the first to identify a novel neutrophil subpopulation, N4, that is closely associated with the progression of cervical cancer. Characterized by high PLAU expression and specific interactions with tumor cells, N4 neutrophils were shown to promote tumor growth and immune modulation.
Ze Wang, Liang Zhuang, Shiyi Liu, Canhui Cao, Shimin Chen, Nan Yu, Xiaoyuan Huang, Tao Zhang   +7 more
wiley   +1 more source