Expression of the stem cell markers NANOG and SOX2 in the cervical squamous carcinogenesis
The aim of the present study was to assess a diagnostic potential of stem cell markers NANOG and SOX2 for classifying cervical squamous intraepithelial lesions (SILs)/cervical intraepithelial neoplasia (CIN).
Koren Miha +4 more
doaj +1 more source
Prevalence of human papillomavirus genotypes in women with normal and abnormal cervical cytology in Iran [PDF]
Introduction: HPV infection has a prime etiologic role in development and progression of cervical cancer, one of the most frequent forms of cancer among women in developing countries.
Dastan, J. +9 more
core
Dynamics of genotype-specific HPV clearance and reinfection in rural Ghana may compromise HPV screening approaches [PDF]
Persistent Human Papillomavirus (HPV) infection is a prerequisite for cervical cancer development. Few studies investigated clearance of high-risk HPV in low-and-middle-income countries.
Adams, Rashid A. +12 more
core +1 more source
Prevention of cervical intraepithelial neoplasia and cervical cancer [PDF]
We review the current status of prevention trials in the management of cervical intraepithelial neoplasia (CIN) and cervical cancer. Two large, randomized controlled trials have shown that folic acid is inactive in reversing low to moderate grade CIN.
Meyskens, F L, Jr, Manetta, A
openaire +5 more sources
This study is the first to identify a novel neutrophil subpopulation, N4, that is closely associated with the progression of cervical cancer. Characterized by high PLAU expression and specific interactions with tumor cells, N4 neutrophils were shown to promote tumor growth and immune modulation.
Ze Wang +7 more
wiley +1 more source
HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann +7 more
wiley +1 more source
Clinical analysis of cervical intraepithelial neoplasia with vaginal intraepithelial neoplasia
The purpose of this prospective cohort study is to evaluate the importance of screening and its diagnostic accuracy compared with the pathological diagnosis of cervical intraepithelial neoplasia (CIN) with vaginal intraepithelial neoplasia (VAIN).The prospective study enrolled 419 patients (pts) and was conducted between February 1, 2015 and January 31,
He, Yue +5 more
openaire +2 more sources
This study establishes the role of high‐risk HPV infection in cutaneous sebaceous carcinoma of the genital area. An intraepithelial component in a subset of cases poses a challenge to distinguish the entity from squamous cell carcinoma in situ. Rarely, sebaceous neoplasia of the genital area is associated with Muir–Torre syndrome. Aims This study aimed
Katharina Wiedemeyer +5 more
wiley +1 more source
The HPV cellular transactivator Brn-3a can be used to predict cervical adenocarcinoma and squamous carcinoma precancer lesions in the developed and developing worlds [PDF]
The cellular transactivator Brn-3a has previously been shown to be expressed at elevated levels in the cervix of women with squamous cell carcinoma of the cervix (SCC) and to activate the expression of HPV E6 mRNA.
Khan, A. +5 more
core +3 more sources
Abstract Objectives Superficial esophageal squamous cell carcinoma (ESCC) detection is crucial. Although narrow‐band imaging improves detection, its effectiveness is diminished by inexperienced endoscopists. The effects of artificial intelligence (AI) assistance on ESCC detection by endoscopists remain unclear.
Naoki Aoyama +6 more
wiley +1 more source

