Results 81 to 90 of about 26,358 (196)

Goniothalamin as a Styryl‐Lactone Toxicophore in Cancer Models: Electrophile‐Driven DNA Damage, Reactive Oxygen Species–Endoplasmic Reticulum Stress Signaling and Detoxification‐Relevant Safety Considerations

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Goniothalamin (GTN) exerts anticancer effects by promoting reactive oxygen species (ROS) generation, glutathione (GSH) depletion, DNA damage, endoplasmic reticulum (ER) stress, and mitochondrial dysfunction. These interconnected events trigger apoptosis, necroptosis, anoikis, and autophagy, while modulating mitogen‐activated protein kinase (MAPK ...
Nataša Joković, Strahinja Pešić, Marija Novaković, Anđela Dubroja Krstić, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

Cervical intraepithelial neoplasia and cervical cytology in pregnancy

Journal of Pathology and Translational Medicine
Cervical cancer screening during pregnancy presents unique challenges for cytologic interpretation. This review focuses on pregnancy-associated cytomorphological changes and their impact on diagnosis of cervical intraepithelial neoplasia (CIN) and cervical cancer.
Ji-Young Kim, Jeong Yun Shim
openaire   +3 more sources

Glucose Transporter 1 in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai, Zhihao Chen, Yuping Zhu, Weidong Han   +3 more
wiley   +1 more source

Human Papilloma Virus and Squamous Cell Carcinoma of the Anus

Clinical Medicine Insights: Oncology, 2014
The incidence of anal cancer is increasing. In the UK, the incidence is estimated at approximately 1.5 per 100,000. Most of this increase is attributed to certain at-risk populations.
Bhavna Gami, Faris Kubba, Paul Ziprin
doaj   +1 more source

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

VIEW Medicine, Volume 1, Issue 1, August 2026.
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng, Qing Cong, Ling Lin, Liang Qiao   +3 more
wiley   +1 more source

Gynaecologists' Views and Acceptability of Active Surveillance for Women Diagnosed With Cervical Intraepithelial Neoplasia 2: A Qualitative Study

Australian and New Zealand Journal of Obstetrics and Gynaecology, Volume 66, Issue 4, August 2026.
ABSTRACT Background Persistent oncogenic HPV infection can cause cervical epithelial changes leading to premalignant lesions such as CIN2. Active surveillance, a conservative option, reduces exposure to excisional risks while allowing timely treatment when needed. However, little is known about clinicians' perspectives, acceptability, and experience of
Dan Luo, Ashleigh R. Sharman, Deborah Bateson, Megan Smith, Kirsten I. Black, Katy Bell, Kirsten J. McCaffery, Rachael H. Dodd   +7 more
wiley   +1 more source

A Comparative Study Between Pap Smear and Visual Inspection with Acetic Acid in Screening of Cervical Intraepithelial Neoplasia and Cervical Cancer at a Tertiary Maternity Hospital (Erbil/Iraq)

Advanced Medical Journal
Background and objectives: Global concern persists over cervical cancer, demanding efficient early detection methods. The aim of the study was to assess the diagnostic efficacy of Pap smear and visual inspection with acetic acid in detecting cervical ...
Shkofa Khalid Mohammed, Trifa Yousif Mutalib   +1 more
doaj   +1 more source

Assessing the clinical value of cervical biopsies in individuals with transformation zone type 3 at colposcopy: A cross‐sectional study

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1597-1606, August 2026.
In transformation zone type 3, a systematic multiple biopsy protocol improved CIN2+ detection, particularly in high‐grade referrals, whereas yield remained limited in low‐grade referral cases. DSI‐assisted colposcopy did not increase biopsy sensitivity’.
Vibe Munk Bertelsen, Berit Bargum Booth, Mette Tranberg, Lone Kjeld Petersen, Pinar Bor   +4 more
wiley   +1 more source

Cervical intraepithelial neoplasia.

BMJ, 1988
D, Jenkins, M H, Jones
  +8 more sources

Laparoscopic Transabdominal Cerclage Despite the Absence of Prior Pregnancy Loss: A Case of Profound Acquired Cervical Anatomical Defects After Repeated Conization

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 8, August 2026.
ABSTRACT Repeated cervical conization can result in cervical shortening and substantial structural and functional impairment. A 35‐year‐old woman developed cervical stenosis and hematometra after undergoing two conizations. The vaginal cervix and external os were unidentifiable, drainage was unsuccessful, and laparoscopy‐assisted recanalization proved ...
Kensuke Suzuki, Takayuki Iriyama, Gentaro Izumi, Osamu Hiraike, Miyuki Harada, Yasushi Hirota   +5 more
wiley   +1 more source