Results 181 to 190 of about 2,510,677 (328)

Unveiling the expression and mechanistic role of SYCP2 in cervical lesions. [PDF]

Discov Oncol
Zhu Y, Hou Z, Wang C, Hu H, Zhang Z, Yang X, Liu L, Ren C.   +7 more
europepmc   +1 more source

Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions

, 2007
L. Villa, Gonzalo Pérez, S. Kjaer, J. Paavonen, M. Lehtinen, N. Muñoz, K. Sigurdsson, M. Hernández-Ávila, F. Skjeldestad, S. Thoresen, P. García, S. Majewski, J. Dillner, S. Olsson, H. T. Eng, F. Bosch, K. Ault, Darron R. Brown, D. Ferris, L. Koutsky, R. Kurman, E. Myers, E. Barr, J. Boslego, J. Bryan, M. Esser, C. Gause, T. Hesley, L. Lupinacci, H. Sings, F. Taddeo, A. R. Thornton   +31 more
semanticscholar   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Dysbiosis of vaginal and peritoneal fluid microbiota in patients with cervical lesions. [PDF]

BMC Womens Health
Zhu L, Wu Z, Shi S, Xue H, Zhen L, Wang Y, Huang J, Liu S, Yi H.   +8 more
europepmc   +1 more source

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

Advanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke, Tania Kamal, Taylor E. Divita, Artem N. Pachikov, Chad A. LaGrange, Rajesh Ravichandran, Martha Morton, Robert Powers, Haowen Qiu, Jean‐Jack M. Riethoven, Colm Morrissey, Melinda Wojtkiewicz, Rebekah L. Gundry, Carol A. Casey, Armen Petrosyan   +14 more
wiley   +1 more source

The dual role of vulvovaginal candidiasis in HPV infection: implications for vaginal microecology and cervical lesions. [PDF]

Front Microbiol
Zhang X, Yao M, Huang Y, Wang H, Li H, Ma J.   +5 more
europepmc   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

Advanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen, Zening Huang, Rui Chang, Wei Gao, Yajing Qiu, Bin Sun, Chen Hua, Xiaoxi Lin   +7 more
wiley   +1 more source

Prevalence of Noncarious Cervical Lesions and Gingival Recession in Subpopulations of Guinea-Bissau. [PDF]

Int J Dent
da Rocha PG, Moreira DM, de Menezes AST, Teixeira AKM, de Paula Freitas JV, Neri JR, Sousa FB, Sousa RMRB, de Souza SLX, de Barros Silva PG, de Aguiar Filgueira A, Lima RA, Cunha DA, Vieira-Meyer APGF.   +13 more
europepmc   +1 more source

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

Advanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan, Weijia Li, Wenxue Huang, Jilin Wu, Yao Yu, Yiyao Huang, Lin Yang, Ming Xie, Qishen Yang, Jun Zheng, Yuexuan Zhu, Qi Sun, Biao Li, Leqian Li, Zongwei Wang, Jie Zhao, Peng Wu, Bisheng Cheng   +17 more
wiley   +1 more source

Precancerous Cervical Lesions in HIV-Positive Women: Caution Needed in Interpreting Low Prevalence Estimates. [PDF]

Health Sci Rep
Tahir I, Shahbaz H, Khattak A.
europepmc   +1 more source