Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert +5 more
wiley +1 more source
Development and clinical validation of a clinically translatable non-chip-on-tip transvaginal imaging system (GynoSight v2.0) for early detection of premalignant cervical lesions. [PDF]
J Biomed OptJeyachandran K +8 more
europepmc +1 more source
Novel planning pipeline utilizing the Surgical Theater system for pediatric epilepsy surgery
Epilepsia Open, EarlyView.Abstract Objective Advances in the analysis and collation of radiographic datasets have enhanced presurgical planning for various neurosurgical procedures, including clipping of cerebral aneurysms, surgical resection of tumors, and arteriovenous malformation management.
Lisa B. E. Shields +4 more
wiley +1 more source
HPV genotype distribution and cervical lesions in Chongqing: a comprehensive analysis of 229,770 females (2015‒2023). [PDF]
BMC Infect DisDing H, Jin H, Tang Y.
europepmc +1 more source
H/M-ratio in spasticity before and after therapy with vibration impulses [PDF]
, 1988 Krause, Klaus-Henning +2 more
core
Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content
Food Safety and Health, EarlyView.By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao +8 more
wiley +1 more source
Fine-grained pathomorphology recognition of cervical lesions with a dropped multibranch Swin Transformer. [PDF]
Quant Imaging Med SurgCheng Y +6 more
europepmc +1 more source
Quality of Life After Surgical Treatment of Head and Neck Paragangliomas
Head &Neck, EarlyView.ABSTRACT Background Head and neck paragangliomas (HNPGLs) are rare neuroendocrine tumors and often arise in the head and neck. Due to their localization, the tumor and its surgical treatment pose a risk for cranial nerve impairments. Few studies have focused on the health‐related quality of life (HRQOL) in patients with HNPGLs and their relation to ...
Christina Sauter +5 more
wiley +1 more source
The diagnostic of PAX1 gene methylation in cervical lesions and its role in the triage of non-16/18 HR-HPV positive. [PDF]
Front ImmunolChen MM +8 more
europepmc +1 more source
Head &Neck, EarlyView.ABSTRACT Background Postoperative adjuvant therapy strategies are generally determined based on pathological risk stratification in oral cancer. However, the efficacy of postoperative adjuvant therapy in patients with intermediate‐risk factors for recurrence of oral cancer such as close surgical margins, pT3–T4 classification, pN2–N3 nodal status ...
Koichi Koizumi +7 more
wiley +1 more source