Results 61 to 70 of about 2,510,677 (328)

The vaginal microbiota associates with the regression of untreated cervical intraepithelial neoplasia 2 lesions

Nature Communications, 2020
Emerging evidence suggests associations between the vaginal microbiota (VMB) composition, human papillomavirus (HPV) infection, and cervical intraepithelial neoplasia (CIN); however, causal inference remains uncertain.
A. Mitra, D. MacIntyre, G. Ntritsos, Ann Smith, K. Tsilidis, J. Marchesi, P. Bennett, A. Moscicki, M. Kyrgiou   +8 more
semanticscholar   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Coexistence of Cervical Leiomyosarcoma and Gastric-Type Adenocarcinoma In Situ with Extensive Extension to the Endometrium and Fallopian Tube

Case Reports in Pathology, 2018
Cervical leiomyosarcoma is known to be rare from the previous reviews of a large number of malignant cervical tumors. The patient was a 66-year-old woman with irregular vaginal bleeding.
Ayako Ura, Kanako Ogura, Asumi Sakaguchi, Hiroko Onagi, Daiki Ogishima, Yayoi Sugimori, Kensuke Hamamura, Masaharu Fukunaga, Toshiharu Matsumoto   +8 more
doaj   +1 more source

Associations of multi-human papillomavirus infections with expression of p16 in a cohort of women who underwent colposcopy: a retrospective study of 5165 patients

Frontiers in Oncology, 2023
ObjectiveInvestigate HPV types in cervical specimens, their correlation with p16 expression in lesions, and diagnostic value for cervical lesions. Enhance clinical diagnosis reliability.MethodsRetrospective cross-sectional study at Fujian Maternity and ...
Yulong Zhang, Haibo Li, Xiaowen Li, Zelong Li, Qianru You, Hanwen Liu, Zhiyan Zhao, Yanzhao Su, Xiangqin Zheng, Yusha Chen, Jiancui Chen, Huan Yi   +11 more
doaj   +1 more source

Public health approach to prevent cervical cancer in HIV-infected women in Kenya : issues to consider in the design of prevention programs [PDF]

, 2017
Women living with HIV in Africa are at increased risk to be co-infected with Human Papilloma Virus (HPV), persistent high risk (HR) HPV infection and bacterial vaginosis (BV), which compounds HPV persistence, thereby increasing the risk for cervical ...
Callens, Steven, Harmon, Stacy G, Mabeya, Hillary, Menon, Sonia, Rossi, Rodolfo   +4 more
core   +3 more sources

Glass Ionomer Cements for the Restoration of Non-Carious Cervical Lesions in the Geriatric Patient

Journal of Functional Biomaterials, 2018
Background: The restoration of non-carious cervical lesions in geriatric patients is a demanding process. Glass ionomer cements can be promising materials for the management of these lesions in older adults.
Nikolaos-Stefanos Kampanas, M. Antoniadou   +1 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Prevalence and Risk Factors of Cervical Lesion Among Married Women With Low Socioeconomic Status: A Study Based on a Cervical Cancer Screening Program

International Journal of Public Health
ObjectivesThis study aimed to investigate the prevalence of cervical lesions in married women with low socioeconomic status, and the related risk factors to provide evidence for the development of cervical cancer prevention strategies.MethodsDescriptive ...
Mingyu Zhang, Mingyu Zhang, Haoyue Wang, Haoyue Wang, Ruoxi Ding, Wen Li, Ping He, Hui Li, Hui Li   +8 more
doaj   +1 more source

Human Pappilomavirus Genotype in Cervical Tissue of Patients with Cervical Intraepithelial Neoplasia (CIN) 1, CIN 2, and CIN 3 [PDF]

, 2016
Objectives: to determine the genotype of HPV in patients with precancerous lesions of cervical tissue.Materials and Methods: An observational study with cross sectional study of patients paraffin block CIN1, CIN2, CIN3 was conducted in Dr Soetomo ...
Alia, R. (Rahmi), I’tishom, R. (Renny), Mastutik, G. (Gondo), Rahaju, A. S. (Anny), Rahniayu, A. (Alphania)   +4 more
core   +1 more source

Extraoral Osseous Choristoma in the Head and Neck Region: Case Report and Literature Review [PDF]

, 2019
An osseous choristoma is a benign tumor consisting of regular bone tissue in an irregular localization. Choristomas in the head and neck region are rare. Most frequently, they are found in the region of the tongue or oral mucosa. There are also very few
Arens, Philipp, Olze, Heidi, Uecker, Florian Cornelius, Ullrich, Andrea   +3 more
core   +1 more source