Results 181 to 190 of about 12,878 (280)

Effect of vaginal pH on the efficacy of the dinoprostone vaginal insert for cervical ripening in patients with an unfavorable bishop score. [PDF]

Rev Bras Ginecol Obstet
Serrano S, Martins I, Gato M, Simões C, Fonseca A, Ferreira H, Centeno M.   +6 more
europepmc   +1 more source

Delivery Mode after Cervical Ripening Among Patients with No Prior Vaginal Births

Inna Bleicher, Marianna DASHKOVSKY-FELDGORN, Shlomi Sagi, Ola Gutzeit, Lihi BLUMEN, Naama Farrago, Nizar Khatib, Yaniv Zipori, Dana Vitner   +8 more
openalex   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Monocytes and cervical ripening: a narrative review of prolonged labor pathophysiology. [PDF]

Ann Med Surg (Lond)
Obeagu EI, Mahmoud SA.
europepmc   +1 more source

A Review of the Mechanism of Action and Clinical Applications of Osmotic Dilators for Cervical Ripening in the Induction of Labor and in Gynecology Procedures. [PDF]

Med Sci Monit, 2023
Socha MW, Flis W, Wartęga M, Kunicka A, Stankiewicz M.   +4 more
europepmc   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Outpatient cervical ripening with Foley balloon or mifepristone: Insights into the time taken to reach the active phase of labor. [PDF]

Int J Gynaecol Obstet
Carvalho-Afonso M, Antunes M, Fonseca A, Ayres-de-Campos D.   +3 more
europepmc   +1 more source

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

Advanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto, Tristan Dellazizzo Toth, Silvano Bond, Alexander Schmitz, Rim Diab, Sara Y. Ngo Tenlep, Brian Mooney, Silvia Erni, Martina Schobesberger, Olivier Scheidegger, Camille Peitsch, Smita Saxena   +11 more
wiley   +1 more source

Comparative Study of the Effectiveness of Double Priming Agents in Cervical Ripening and Induction of Labor in Nulliparas. [PDF]

Cureus
Peethambaran P, Seth I, Vikram A, Madhusoodanan HK, Sharma D.   +4 more
europepmc   +1 more source

Comparison of delivery outcomes in low-dose and high-dose oxytocin regimens for induction of labor following cervical ripening with a balloon catheter: A retrospective observational cohort study

, 2022
Heidi Kruit, Irmeli Nupponen, Seppo Heinonen, Leena Rahkonen   +3 more
openalex   +1 more source