Results 131 to 140 of about 163,432 (256)

β‐Elemene Rescues Radiation‐Induced Enteritis by Orchestrating a Host‐Microbiome Circuit That Fuels Epigenetic DNA Repair

Advanced Science, EarlyView.
This study elucidates that β‐elemene promotes cellular uptake of L. gasseri‐derived lactate by enhancing the membrane translocation of MCT1 in a CD147‐dependent manner. Intracellular lactate, through the lactylation of RBBP4 at the K26 site, recruits EP300 to the promoter regions of downstream genes (POLD1/POLD3), catalyzing H3K27ac modification.
Jiancheng He, Jiapeng Bao, Shukang Deng, Weijie Zang, Haoming Yan, Zihao Zhao, Guangze Zhang, Ruiqing Liu, Junjie Chen, Yilin Hu, Wanjiang Xue   +10 more
wiley   +1 more source

Molecular triage on HPV-positive samples in a cervical screening setting. [PDF]

PLoS One
Larsson GL, Carlsson J, Helenius G, Bergengren L.   +3 more
europepmc   +1 more source

Light‐Activatable Nitric Oxide Release via Intramolecular Electron Transfer for Tumor Pyroptosis Induction

Advanced Science, EarlyView.
This work proposes a novel strategy to fabricate unimolecular pyroptosis photoinitiators activated by deep‐red light at low light doses. It relies on a photosensitization mechanism to trigger nitric oxide (NO) release from benzisothiadiazole‐based N‐nitrosanilines without modification of nitro moieties, thereby boosting pyroptosis‐mediated ...
Chuangxin Zhang, Ruipeng Li, Yunxia Wang, Feng Liu, Liheng Feng   +4 more
wiley   +1 more source

Understanding preferences for self-sampling in a national cervical screening programme: a protocol for a discrete choice experiment. [PDF]

BMJ Open
Thapa S, Davies JC, Crosbie EJ, Payne K, Wright S.   +4 more
europepmc   +2 more sources

Investigating the Acceptability of Cervical Screening and Self-Sampling in Postnatal Women at the 6-Week Postnatal Check-Up: A Qualitative Study. [PDF]

Health Expect
Newhouse R, McWilliams L, Baker-Rand H, Cullimore V, Davidson E, Sundar S, Morrison J.   +6 more
europepmc   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Cervical Screening Systems in Eastern Europe and Central Asia: A Comparative Policy Evaluation. [PDF]

Healthcare (Basel)
Ussai S, Seyidov T, Blanqué Catalina N, Khomasuridze T, Regional Alliance for Cervical Cancer Prevention in EECA (the “Alliance”).   +4 more
europepmc   +1 more source

Cervical Cancer Screening [PDF]

Journal of Midwifery & Women's Health, 2015
openaire   +2 more sources

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Health care policy trial of primary human papillomavirus-based cervical screening in Denmark: Comparison of three triage algorithms. [PDF]

Int J Cancer
Schroll JB, Bonde J, Lynge E, Waldstrøm M, Viborg PH, Frandsen A, Andersen RH, Nielsen SM, Kristensen BK, Schledermann D, Andersen B, National Danish Cervical Cancer Screening Steering Committee.   +11 more
europepmc   +1 more source