Results 201 to 210 of about 1,494,574 (301)

Qualitative insights into the acceptability of self-collection for cervical screening amongst under- and never-screened groups in Australia. [PDF]

BMC Public Health
Jops P, Wolter A, Bavor C, Dodd R, Smith MA, Saunders T, Nightingale C, Kelly-Hanku A.   +7 more
europepmc   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Why do the Nordic countries allow colposcopy to be a weak link in the cervical cancer screening chain?

Acta Obstetricia et Gynecologica Scandinavica
Ilkka Kalliala, Hanna Milerad, Ameli Ellen Claesdotter Trope, Anne Hammer   +3 more
doaj   +1 more source

Loop electrosurgical excision procedure and perinatal outcomes post-human papillomavirus cervical screening: A longitudinal cohort study. [PDF]

Int J Gynaecol Obstet
Hong Q, Smith LW, Proctor L, Gondara L, Alam S, Cook D, Franco EL, Krajden M, Martin RE, McClymont E, Melnikow J, Peacock S, Stuart G, Ogilvie GS, Gottschlich A.   +14 more
europepmc   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Molecular triage on HPV-positive samples in a cervical screening setting. [PDF]

PLoS One
Larsson GL, Carlsson J, Helenius G, Bergengren L.   +3 more
europepmc   +1 more source

Inorganic Nanomaterials can Promote or Inhibit Tumor Metastasis Depending on Tumor Microenvironment Composition

Advanced Science, EarlyView.
As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens, Xiaoqi Zheng, Xueqi Fan, Mukaddes Izci, Christy Maksoudian, Irati Perez Gilabert, Tianjiao Chu, Filipa Goncalves, Jonas Dehairs, Johan Swinnen, Bella B. Manshian, Stefaan J. Soenen   +11 more
wiley   +1 more source

Co-designing solutions to promote awareness of cervical screening with women of low socio-economic position living in urban areas. [PDF]

BMC Public Health
Mulcahy Symmons S, Drury A, Darley A, Kroll T, De Brún A.   +4 more
europepmc   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Perceived barriers and facilitators to conventional cervical screening: a qualitative study among women, primary health workers and community representatives in Uganda. [PDF]

BMC Health Serv Res
Nanyonjo G, De Paepe E, Wambuzi M, Kasule S, Okech B, Ssetaala A, Vermandere H, Degomme O.   +7 more
europepmc   +1 more source