Results 21 to 30 of about 81,778 (253)
OBJECTIVE: This study aimed to systematically review the worldwide second-stage cesarean delivery rate concerning pre–second-stage cesarean delivery and assisted vaginal birth rates.
Lin Tai Linus Lee, MRCOG +11 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah +6 more
wiley +1 more source
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu +18 more
wiley +1 more source
A Risk Score for Predicting Postpartum Hemorrhage in Association with Cesarean Delivery
Objective:To determine the prevalence of postpartum hemorrhage (PPH) in association with cesarean delivery and to develop a risk score for predicting PPH in women who underwent cesarean delivery based on clinical characteristics.Methods ...
Jurarut Suta +2 more
doaj +1 more source
The Relevance of the Second Cesarean Delivery in the Reduction of Institutional Cesarean Delivery Rates [PDF]
<b><i>Objective:</i></b> The cesarean delivery rate has increased worldwide. The aim of our study was to assess the events associated with the second cesarean deliveries in our institution. <b><i>Subjects and Methods:</i></b> All cesarean deliveries at the Maternity Hospital, Kuwait, from January 1 to ...
Michael F E, Diejomaoh +4 more
openaire +2 more sources
This study analyzed nationwide trends, demographic characteristics, and seasonal patterns of rectal prolapse surgery in Japan using healthcare claims data. From 2014 to 2023, age‐adjusted overall and conventional surgeries declined significantly, whereas laparoscopic surgeries increased significantly.
Masamitsu Kido +9 more
wiley +1 more source
Risk adjustment in maternity care: the use of indirect standardization
James M NicholsonDepartment of Family Practice and Community Medicine, University of Pennsylvania Health System, University of Pennsylvania, Philadelphia, PA, USAPurpose: Annual US national rates of family physicians providing maternity care are ­
James M Nicholson
doaj
Prenatal Evaluation of RNU4‐2 Variants in Fetuses With Central Nervous System Anomalies
ABSTRACT Fetal central nervous system (CNS) anomalies are among the most common congenital malformations, yet the overall prenatal diagnostic yield of current genetic testing remains below 40%. Variants in RNU4‐2, a non‐coding gene encoding the U4 small nuclear RNA (snRNA), have recently been linked to a novel highly recurrent dominant ...
Yiyao Chen +13 more
wiley +1 more source

