Results 61 to 70 of about 167,804 (307)

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Calibrazione del modello CFD di una turbina Kaplan [PDF]

, 2022
Studio CFD stazionario di una turbina Kaplan in condizioni di collaudo e di ...
Simonini, Alberto
core  

Living together, sometimes feeding in a similar way: the case of the syntopic hylid frogs Hypsiboas raniceps and Scinax acuminatus (Anura: Hylidae) in the Pantanal of Miranda, Mato Grosso do Sul State, Brazil Vivendo juntos e algumas vezes alimentando-se de forma semelhante: o caso das pererecas sintópicas Hypsiboas raniceps e Scinax acuminatus (Anura: Hylidae) no Pantanal do Miranda, Mato Grosso do Sul, Brasil

Brazilian Journal of Biology, 2010
We studied the feeding ecology of two Hylinae anurans (Hypsiboas raniceps and Scinax acuminatus), living sympatrically and syntopically in the Pantanal of Miranda, Mato Grosso do Sul State, Brazil.
LT. Sabagh, VL. Ferreira, CFD. Rocha
doaj   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

FSSteering: A Distributed Framework for Computational Steering in a Script-based CFD Simulation Environment [PDF]

, 2010
In order to get insight into interesting flow phenomena, the traditional work-flow of computational fluid dynamics (CFD) consists of setting up and computing the flow field followed by a consecutive post-processing analysis.
Gerndt, Andreas, Flatken, Markus, Hagen, Hans, Wagner, Christian, Meinel, Michael   +4 more
core  

CFD Study on Hydrogen-Air Premixed Combustion in a Micro Scale Chamber [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2010
This paper reports a CFD modeling study to investigate the hydrogen-air mixture combustion in a micro scale chamber. Nine species with nineteen reversible reactions were considered in the premixed combustion model.
Sayed Reza Shabanian, Masoud Rahimi, Abbas Khoshhal, Ammar Abdulaziz Alsairafi   +3 more
doaj  

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

CFD-online-forums-analysis: v1.0 [PDF]

, 2015
Counting numbers of threads and posts on the CFD Online ...
Pete Bachant
core   +1 more source

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

Advanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun, Anna Paříková, Sandra Rother, Martin Kantor, Salman Muhammad Ilyas, Ricardo Bernhardt, Pavel Ndjawa Yomi, Jaromír Havlica, Revathi Appali, Benjamin Kruppke, Poh Soo Lee   +10 more
wiley   +1 more source

Dynamic thermal modelling using CFD [PDF]

, 2003
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Buildings expend vast quantities of energy, which has a detrimental impact on the environment.
Somarathne, Shini
core