Results 1 to 10 of about 2,418 (178)
A conserved WXXE motif is an apical delivery determinant of ABC transporter C subfamily isoforms
Cell Structure and Function, 2023 ATP-binding cassette transporter isoform C7 (ABCC7), also designated as cystic fibrosis transmembrane conductance regulator (CFTR), is exclusively targeted to the apical plasma membrane of polarized epithelial cells.
Md Shajedul Haque +2 more
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Clinical and Experimental Obstetrics & Gynecology, 2022 Background: Cystic Fibrosis (CF) is a genetic disease which is responsible for different systemic conditions. In particular, CF could be responsible for infertility, especially in the male partner due to congenital bilateral absence of vas deferens ...
Elena D’Alcamo +14 more
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A dos metros de ti/Five Feet Apart (2019) de Justin Baldoni
Revista de Medicina y Cine / Journal of Medicine and Movies, 2022 El cine es una efectiva herramienta de enseñanza - aprendizaje que permite ilustrar desde diversos enfoques los procesos complejos de la enfermedad. En este artículo hacemos hincapié sobre estas herramientas educativas que nos brinda la película A dos ...
Natalia Bailon-Moscoso +5 more
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USO DE EXACAFTOR/ TEZACAFTOR /IVACAFTOR EN PACIENTES CON FIBROSIS QUÍSTICA POST-TRASPLANTE PULMONAR
Neumología Pediátrica, 2023 El uso de moduladores de CFTR en pacientes con fibrosis quística post trasplante pulmonar es un tema todavía controversial. Varias publicaciones reportan los beneficios del modulador elexacaftor/tezacaftor/ivacaftor en los síntomas extrapulmonares de la ...
Pablo Jorquera Pinto
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Investigating the Genetic Sequence of Exons and Exon-intron Junction Sequences of CFTR Gene by PCR Method in Families Suspected of Cystic Fibrosis in Khuzestan Province [PDF]
مجله دانشکده پزشکی اصفهان, 2023 Background: Cystic fibrosis is one of the most fatal multisystem disorders and the most common autosomal recessive disease in the white population, which occurs due to mutations in cystic fibrosis membrane regulatory proteins (CFTR).
Leili Delfi Fallah +4 more
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Functional interplay between CFTR and pendrin: physiological and pathophysiological relevance
Frontiers in Bioscience-Landmark, 2022 The transport of chloride and bicarbonate across epithelia controls the pH and volume of the intracellular and luminal fluids, as well as the systemic pH and vascular volume.
Grazia Tamma, Silvia Dossena
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Biomolecules, 2020 Chronic infection and inflammation are the primary causes of declining lung function in Cystic Fibrosis (CF) patients. ORKAMBI® (Lumacaftor-Ivacaftor) is an approved combination therapy for Cystic Fibrosis (CF) patients bearing the most common ...
Onofrio Laselva +3 more
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Liver disease in cystic fibrosis patients in a tertiary care center in Saudi Arabia
International Journal of Pediatrics & Adolescent Medicine, 2022 Background: Internationally, Cystic fibrosis-associated liver disease (CFLD) is considered the third leading cause of death, following lung disease and transplantation complications.
Hanaa Banjar +7 more
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International Journal of Pediatrics & Adolescent Medicine, 2022 Introduction: Meconium ileus (MI) is one of the most common causes of intestinal obstruction in newborns. It is the earliest clinical manifestation of cystic fibrosis (CF). MI is suspected if a baby fails to pass meconium shortly after birth and develops
Hanaa Banjar +4 more
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Analysis of Ivacaftor drug approval for cystic fibrosis patients with gating mutations. [PDF]
The Young Researcher, 2021 Cystic fibrosis is an inherited monogenetic disorder that leads to chronic respiratory and lung infections. These infections result in decreased quality of life in patients.
Nemirajaiah, S.
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