Results 151 to 160 of about 81,604 (317)
This review surveys recent progress in the synthesis of extended aromatic quinolizinium derivatives via intramolecular SNAr and oxidative 6π‐electrocyclization. Conventional thermal approaches are discussed alongside emerging, sustainable activation methods such as electrosynthesis and photochemical processes.
Marine Labro +2 more
wiley +1 more source
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao +2 more
wiley +1 more source
Chloride Sensor Based on Silver Nanoparticles Coupled with a Fast‐Response MOSFET System
A potentiometric sensor based on a MOSFET device (Metal‐Oxide‐Semiconductor Field‐Effect Transistor) and silver nanoparticles (AgNPs) was developed for chloride quantification, offering increased signals, fast response, and efficient data processing, which can be used for monitoring and diagnosis.
Ricardo Antonio Escalona‐Villalpando +9 more
wiley +1 more source
Distribution of CFTR gene mutations in cystic fibrosis patients from Estonia [PDF]
M. Teder +4 more
openalex +1 more source
Mechanical Cues Regulate Cargo Sorting and Export at the Golgi
A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino +21 more
wiley +1 more source
Pharmacogenomics in clinical practice: Biomarker information in Brazilian drug labels
This review examines the PGx annotations in package inserts (bulas in Brazilian Portuguese) approved by ANVISA, the Brazilian Health Regulatory Agency, for 19 gene–drug pairs with strong or moderate recommendations for initial dosing alteration in the CPIC (Clinical Pharmacogenetic Implementation Consortion) guidelines and PGx testing required or ...
Guilherme Suarez‐Kurtz
wiley +1 more source
Cystic fibrosis (CF) is a chronic hereditary disease that affects tens of thousands of people worldwide. The introduction of CFTR modulator therapies such as elexacaftor/tezacaftor/ivacaftor (ETI) has significantly improved the quality of life of people with CF.
Alan Shi +3 more
wiley +1 more source
128. Efficient Transfer of Half-CFTR Modules with a Strong Promoter in AAV Vectors [PDF]
openalex +1 more source
Single‐nucleus RNA sequencing (snRNA‐seq) maps the cellular diversity of pulmonary sarcomatoid carcinoma (PSC) and primary pulmonary sarcomas (PPS). AT2 cells, a major source of epithelial cells in PSC, underwent malignant transformation primarily through epithelial–mesenchymal transition, suggesting AT2 cells may serve as the origin of PSC.
Jianfei Zhu +11 more
wiley +1 more source

