Results 301 to 310 of about 81,604 (317)

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

Proceedings of the National Academy of Sciences of the United States of America, 2009
P D J Grootenhuis
exaly  

Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

Lancet Respiratory Medicine,the, 2015
Deborah Ashby, Katie J Bayfield, Ruaridh Buchan   +2 more
exaly  

CFTR regulates phagosome acidification in macrophages and alters bactericidal activity

Nature Cell Biology, 2006
Chunying Li, Deborah J Nelson
exaly  

Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis

Science Translational Medicine, 2014
Charles R Esther, Nikolay V Dokholyan, Scott H Randell   +2 more
exaly  

CFTR crystals

Trends in Molecular Medicine, 2001
openaire   +1 more source

Some gating potentiators, including VX-770, diminish ΔF508-CFTR functional expression

Science Translational Medicine, 2014
Guido Veit, Puay-Wah Phuan, Miklos Bagdany   +2 more
exaly  

CFTR Physiology

2020
openaire   +1 more source

CFTR Regulation of ENaC

2003
Scott H, Donaldson, Elaine G, Poligone, M Jackson, Stutts   +2 more
openaire   +2 more sources

Ivacaftor treatment of cystic fibrosis in children aged 12 to <24 months and with a CFTR gating mutation (ARRIVAL): a phase 3 single-arm study

Lancet Respiratory Medicine,the, 2018
Margaret Rosenfeld, Claire E Wainwright, Steve Cunningham   +2 more
exaly  

CFTR Degradation and Aggregation

2003
Michael J, Corboy, Philip J, Thomas, W Christian, Wigley   +2 more
openaire   +2 more sources