Results 41 to 50 of about 42,079 (241)

Assessment of Prediction Capabilities of COCOSYS and CFX Code for Simplified Containment

Science and Technology of Nuclear Installations, 2016
The acceptable accuracy for simulation of severe accident scenarios in containments of nuclear power plants is required to investigate the consequences of severe accidents and effectiveness of potential counter measures.
Jia Zhu, Xiaohui Zhang, Xu Cheng
doaj   +1 more source

SPECTROPHOTOMETRIC ANN ATOMIC ABSORPTION DETERMINATION CEFIXIME BY CLOUD POINT EXTRACTION IN PURE FORM

The Iraqi Journal of Agricultural science, 2019
A simple, rapid, accurate, sensitive and ecofriendly method has been developed for the quantitative determination of Cefixime (CFX) in pure form and pharmaceutical preparations by using a combination of cloud point extraction with UV-Visible absorption ...
Dhahir & Mohammed
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Electrochemical studies of ciprofloxacin and its interaction with DNA(环丙沙星与DNA相互作用的电化学研究)

Zhejiang Daxue xuebao. Lixue ban, 2007
研究了环丙沙星(CFX)在自制的浸蜡石墨电极上的电化学特性，示差脉冲伏安法发现CFX在0.88 V处有一明显的氧化峰，DNA的加入使这一氧化峰明显减弱.采用所推导的电化学公式对实验数据进行了非线性拟合，同时获得了CFX与DNA的结合常数（K=1.36105（mol/L）-1）和结合位点数（s= 1.94），并探讨了CFX与小牛胸腺DNA的结合机理.
SHIQiao-cui(时巧翠), WANGSu-fen(王素芬), ZHUBin(朱斌), JIMin(季敏)   +3 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Green Chemometric Determination of Cefotaxime Sodium in the Presence of Its Degradation Impurities Using Different Multivariate Data Processing Tools; GAPI and AGREE Greenness Evaluation

Molecules, 2023
Four eco-friendly, cost-effective, and fast stability-indicating UV-VIS spectrophotometric methods were validated for cefotaxime sodium (CFX) determination either in the presence of its acidic or alkaline degradation products.
Yasmine Ahmed Sharaf, Adel Ehab Ibrahim, Sami El Deeb, Rania Adel Sayed   +3 more
doaj   +1 more source

Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System

Advanced Functional Materials, EarlyView.
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim, Zhuo Feng Lee, Gi‐Dong Sim, Sejoong Kim, Jessie S. Jeon   +4 more
wiley   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Relatively low temperature defluorination and carbon coating in CFx by dimethyl silicone oil/polyethylene glycol for enhancing performance of lithium primary battery

Electrochemistry Communications
Because of the presence of electrochemically inactive C-F2 bond and poor electronic conductivity of C-F, the discharge performance of lithium fluorocarbon (Li/CFx) batteries is limited, despite their extensive use in commercial fields.
Xu Bi, Xiaotong Guo, Wencheng Song, Dandan Shi, Shuyue Tan, Youzheng Sun, Weiye Zhang, Hao Kang, Yanyan Li, Han Dai, Junfeng Zhao   +10 more
doaj   +1 more source

VIVID: A qPCR‐Based Platform for Sensitive and Quantitative In Vivo Tracking of Extracellular Vesicles

Advanced Functional Materials, EarlyView.
This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian, Talin Ebrahimian, Jonathan Miranda O'Connor, Janusz Rak, Stephanie Lehoux, Maryam Tabrizian   +5 more
wiley   +1 more source