Results 161 to 170 of about 25,419 (244)
British Journal of Pharmacology, EarlyView.This study compares the molecular mechanisms of chemotherapy‐related peripheral neurotoxicity of two proteasome inhibitors, bortezomib and carfilzomib, using a multidisciplinary approach to reveal that, alongside shared effects on mitochondria structure and function, the more neurotoxic drug BTZ has specific effects on microtubules and mitochondrial ...
Federico Iseppon +27 more
wiley +1 more source
The use of xenografts with fish skin for the treatment of burns: a systematic review and meta-analysis. [PDF]
Acta Cir BrasArcanjo CPC +3 more
europepmc +1 more source
Optimization of novel compounds using computer‐aided drug design for treatment of cardiac arrhythmia
British Journal of Pharmacology, EarlyView.Background and Purpose Loss‐of‐function mutations of the voltage‐gated Kv7.1 (KCNQ/KCNE1) channels lead to cardiac arrhythmia such as long QT syndrome, characterized by a prolonged QT interval . One strategy to correct the prolonged QT interval is to design molecules that activate KCNQ1/KCNE1 channels and restore the QT interval.
Jessica Jowais +4 more
wiley +1 more source
Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto +121 more
wiley +1 more source
Coronary Artery Disease and Chronic Kidney Disease: A Tale of Two Organs. [PDF]
Arq Bras CardiolKranjec I.
europepmc +1 more source
Assessing patient perception following outpatient dermatological surgical procedures
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and objectives Despite receiving similar information about outpatient dermatologic surgical procedures, some patients still hold misconceptions about the nature of their lesions and the treatment. No studies have been done to understand this difference in the perception of surgery.
Ana Morelló‐Vicente +6 more
wiley +1 more source
U2 snRNP recognizes the branch site through a loaded-spring strand-invasion mechanism. [PDF]
Nucleic Acids ResPokorná P, Pena V, Magistrato A.
europepmc +1 more source
Early neurodevelopmental outcome in newborns with mild hypoxic‐ischaemic encephalopathy
Developmental Medicine &Child Neurology, EarlyView.Aim To describe the natural history of newborn children with mild hypoxic‐ischaemic encephalopathy in the first year of life. Method This was a multicentre, prospective observational study involving five neonatal intensive care units in an Italian region using both structured clinical and neurophysiological assessments according to the Italian Society ...
Domenico M. Romeo +16 more
wiley +1 more source