Results 161 to 170 of about 25,633 (243)

Hybrid grading systems improve progression risk stratification in non‐invasive papillary urothelial carcinoma and support a histomorphological continuum of disease progression

Histopathology, EarlyView.
Hybrid grading systems significantly improve progression‐risk stratification in non‐invasive papillary urothelial carcinoma compared with the WHO 2004/2016 binary classification, with most benefit achieved by a Hybrid 3‐Tier framework. These findings support the existence of a histomorphological continuum of progression risk within the conventional ...
Jane K Nguyen, Marcello P Toscano, Jianbo Li, Sean R Williamson, Christopher G Przybycin, Chia‐Sui Kao, Jonathan L Myles, Kristýna Pivovarčíková, Marián Švajdler, Marek Brousil, Mohamed Eltemamy, Laura Bukavina, Venkatesh Krishnamurthi, Christopher Weight, Rebecca A Campbell, Nima Almassi, Reza Alaghehbandan   +16 more
wiley   +1 more source

Molecular and structural basis of a subfamily of PrfH rescuing both the damaged and intact ribosomes stalled in translation. [PDF]

Sci Adv
Tian Y, Li Q, Fatma S, Jiang J, Jin H, Zeng F, Huang RH.   +6 more
europepmc   +1 more source

A PD1‐CD137L Fusion Protein More Potently Enhances Anti‐Tumour Immune Responses Than Targeting PD‐L1 and CD137 Separately

Immunology, EarlyView.
A PD1‐CD137L fusion protein converts the immunoinhibitory PD‐L1 to an immunostimulatory signal and is more effective than targeting PD‐L1 and CD137 separately. ABSTRACT Tumour immune evasion frequently involves PD‐L1‐mediated inhibition of T cell activity, limiting the efficacy of PD1/PD‐L1 blockade, particularly in PD‐L1‐low or immunologically ‘cold ...
Runze Xia, Emily Pauline Nickles, Yu Mei, Thamizhanban Manoharan, Yi Tian Png, Beijia Liu, Rui Sun, Kang Yi Lee, Gloryn Chia, Chwee Ming Lim, Herbert Schwarz   +10 more
wiley   +1 more source

Application of Digital, Web-Based, and Online Strategies in Point of Care Ultrasound (POCUS) Training: A Scoping Review. [PDF]

Health Sci Rep
Hang J, Maranna S, Parange N, Kumar S.
europepmc   +1 more source

Clinical, Radiographic and Patient‐Centred Outcomes of MINST Versus MIST With Enamel Matrix Derivative in Class II Mandibular Furcation Defects: A Randomised Controlled Trial

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims To evaluate whether minimally invasive non‐surgical therapy (MINST) with flapless application of enamel matrix derivative (EMD) achieves non‐inferior clinical and radiographic outcomes compared to minimally invasive surgical technique (MIST) + EMD, while improving patient‐reported outcome measures (PROMs).
Georgios S. Chatzopoulos, Eleftherios G. Kaklamanos, Ioannis Vouros, Georgios Mikrogeorgis, Aikaterini‐Elissavet Doufexi, Lazaros Tsalikis   +5 more
wiley   +1 more source

Multidimensional Digital Literacy and Quality of Life Among Informal Care Dyads in Malaysia: Cross-Sectional Survey. [PDF]

JMIR Aging
Mohammadzadeh Yazd F, Foong HF, Ibrahim R, Kunasekaran P, Ashari A.   +4 more
europepmc   +1 more source

An Electronic Health Record “Nudge” to Reduce Antipsychotic Medication Prescribing for Primary Care Patients With Dementia: A Pragmatic RCT

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background We hypothesized that an electronic health record (EHR) alert grounded in behavioral science could reduce new antipsychotic medication prescriptions for older adults with dementia. Methods We conducted a pragmatic clinical trial at a large academic health system, randomizing providers to receive the alert (intervention) or not ...
Catherine A. Sarkisian, Chad Wes Villaflores, Anne M. Walling, Sitaram S. Vangala, Eric M. Cheng, Suzanne Bliven Shu, Ajaya Pillai, Grace Y. Cheng, Noah Goldstein, John Mafi   +9 more
wiley   +1 more source

Publisher Correction: Multi-ancestry genome-wide association analyses of refractive error augment genetic discovery and polygenic prediction. [PDF]

Nat Genet
Cheng FF, Liu X, Mi H, Wang L, Ma R, Guo Y, Sidorenko J, Jiang C, Islam T, Meguro A, Hikino K, Ishikawa Y, Tang S, Li T, Chen R, Wang L, Mägi R, Metspalu A, Estonian Biobank Research Team, 23andMe Research Team, Takeuchi M, Mizuki N, Choquet H, Jin ZB, Chen G, Zhou K, Terao C, Zeng J, Yang J.   +28 more
europepmc   +1 more source

GloBIAS survey results – An insight into the global bioimage analysis community

Journal of Microscopy, EarlyView.
Abstract There is a global need for bioimage analysis (BIA) as advances in life sciences increasingly rely on cutting‐edge imaging systems that have dramatically expanded the complexity and dimensionality of biological images. Turning these data into scientific discoveries requires scientists with effective data management skills and knowledge of state‐
Laura R. de la Ballina, Christa G. Walther, Nicholas D. Condon, Alessandro A. Felder, Martin Schätz, Bettina Schmerl, Ko Sugawara, Clara Prats, Anna Klemm, Kota Miura, Paula Sampaio, Christian Tischer, Shuichi Onami, Rocco D'Antuono, Beth A Cimini, Robert Haase, Agustin A. Corbat, Florian Levet   +17 more
wiley   +1 more source

Effectiveness of Digital Serious Games on Knowledge and Attitudes in Public Health Education: Systematic Review and Bayesian Network Meta-Analysis of Randomized Controlled Trials. [PDF]

J Med Internet Res
Huang D, Wu D, Hexel R, Brown-Wilson C, Zhou J, Moyle W.   +5 more
europepmc   +1 more source