Results 181 to 190 of about 25,419 (244)

Water, water, every where—the advent of hydrated pili structure

open access: yesThe FEBS Journal, EarlyView.
Protein structure is defined by its surrounding water. Naturally, this is also true for the gigantic protein filaments that pathogenic bacteria use to attach to and colonize their host cells. Structures of these filaments for which water can be identified with high confidence have stayed elusive for the longest time.
Hiroya Oki   +3 more
wiley   +1 more source

AEROBIC EXERCISE ATTENUATES HEPATIC LIPID PEROXIDATION IN AN EXPERIMENTAL MODEL OF OBESITY-ASSOCIATED NAFLD. [PDF]

open access: yesArq Gastroenterol
Lima MLRP   +6 more
europepmc   +1 more source

Real‐World Unmet Treatment Needs for Patients With Haemophilia: Results From the Global Adelphi Disease Specific Programme Database

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Prophylactic factor replacement and non‐factor therapy has improved bleed prevention and clinical outcomes for people with haemophilia (PwH). The remaining burdens faced by PwH in real‐world settings, despite availability of newer therapies, are not well documented.
Víctor Jiménez Yuste   +5 more
wiley   +1 more source

Mortality trends for diabetes mellitus, hypertension and cardiovascular disease among people living with and without HIV in Brazil during the COVID‐19 pandemic, 2020–2022

open access: yesHIV Medicine, EarlyView.
Abstract Introduction People living with HIV (PLWH) face an increasing burden of non‐AIDS‐related chronic conditions. However, how the COVID‐19 pandemic affected chronic disease‐related mortality in this population remains unclear. We assessed changes in mortality among PLWH in Brazil during the COVID‐19 pandemic.
Tatyellen Natasha da Costa Oliveira   +7 more
wiley   +1 more source

Hodgkin and non‐Hodgkin lymphomas in the post‐antiretroviral therapy era according to HIV virological suppression

open access: yesHIV Medicine, EarlyView.
Abstract Objectives Lymphomas remain among the most frequent HIV‐associated malignancies, with risk persisting despite effective virological control. This study describes the clinical, epidemiological and prognostic characteristics of lymphomas (both Hodgkin [HL] and non‐Hodgkin [NHL]) in people living with HIV (PLWH), according to virological ...
Teresa Aldámiz‐Echevarria   +555 more
wiley   +1 more source

Optimization of Analytical Performances and Routine Laboratory Implementation of NPM1 Mutation Detection by Digital PCR in the Diagnosis and Monitoring of NPM1‐Mutated Acute Myeloid Leukemias

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Quantification and monitoring of NPM1 mutations represent a key tool in the management of acute myeloid leukemia (AML), offering strong prognostic value and serving as a marker of minimal residual disease (MRD). Digital PCR (dPCR) provides absolute quantification with high sensitivity and specificity, offering advantages over ...
Ferrari Chloé   +10 more
wiley   +1 more source

Preparing Emergency Medicine Residents for the Certifying Exam: A Pilot Study of a Longitudinal Simulation-Based Assessment Program. [PDF]

open access: yesAEM Educ Train
Yee J   +13 more
europepmc   +1 more source

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