Safety of upadacitinib in atopic dermatitis in randomized clinical trials across 6 years
Journal of the European Academy of Dermatology and Venereology, EarlyView.The current study found no evidence of cumulative increased safety risks with upadacitinib 15 or 30 mg for up to 6 years and over 9000 patient‐years of safety data in adults and adolescents. There were low rates of adjudicated major adverse cardiovascular events, adjudicated thromboembolic events and malignancies. Abstract Background Atopic dermatitis (
Christopher G. Bunick +13 more
wiley +1 more source
A common structural mechanism for RNA recognition by the SF3B complex in mRNA splicing and export. [PDF]
Nucleic Acids ResZhang Y +8 more
europepmc +1 more source
Especiación química del aerosol orgánico con alta resolución temporal (TAG-CG-EM)
, 2020 openaire +1 more source
Effects of Membrane Cholesterol on the Structure and Function of Selected Class A GPCRs─Challenges and Future Perspectives. [PDF]
BiochemistryChristofidi M +3 more
europepmc +1 more source
Composição química do óleo essencial de (Lippia sp.), nativa do semi-árido brasileiro. [PDF]
, 2012 CASTANHA, R. F. +4 more
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Journal of the European Academy of Dermatology and Venereology, EarlyView.This pan‐European study reveals high rates of addiction in patients with chronic skin diseases. Smoking, alcohol, drug use, gambling, and internet addiction were prevalent and associated with quality of life, demographics, and region. The findings support integrating addiction screening into dermatologic care to improve outcomes.
Stefanie Ziehfreund +73 more
wiley +1 more source
Lauric acid modulates the cyclooxygenases and nitric oxide pathways and reduces oxidative stress in preventing tracheal hyperresponsiveness in asthmatic Wistar rats. [PDF]
Front PharmacolFigueiredo IAD +11 more
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Journal of Fish Biology, EarlyView.Abstract Genomic resources, new microsatellite markers and a novel observation of a fractal pattern in the genetic population structure are presented for curimba, Prochilodus lineatus, a freshwater migratory model species of South America. Our main goals were to investigate the presence of mixed fish stocks and the effects of damming‐induced ...
Gabriel M. Yazbeck +5 more
wiley +1 more source
Impact of opioid-free anesthetic on postoperative complication following gynecological surgery: a meta-analysis. [PDF]
Rev Esc Enferm USPYang L, Tu F.
europepmc +1 more source