The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova +12 more
wiley +1 more source
Learning Classic Grounded Theory: An Account of the Journey and Advice for New Researchers
Graduate students who employ CGT for their theses or dissertations predominantly learn the methodology on their own. As a distinct methodology, CGT is challenging to employ.
Carol Roderick, Ph.D.
doaj
ABSTRACT Individuals with prenatal alcohol exposure (PAE) and fetal alcohol spectrum disorders (FASDs) present a range of neurodevelopmental deficits (e.g., inattention, hyperactivity, and executive dysfunction) which have shown marked overlap with attention‐deficit/hyperactivity disorder (ADHD), making differential diagnosis challenging.
Todd J. Capes +5 more
wiley +1 more source
Rhizobacteria‐Induced Systemic Priming Against Fungal Pathogens Involves Hydroxycinnamic Acid Amides
ABSTRACT The rhizosphere, a narrow region of soil surrounding roots, contains diverse microorganisms with a composition that is distinct from the surrounding soil. Some rhizosphere bacteria can trigger a heightened state of immunity in the whole plant, termed Induced Systemic Resistance (ISR).
Mackenzie Eli William Loranger +5 more
wiley +1 more source
The status of cell and gene therapy education in medical schools-An international survey. [PDF]
Wappler-Guzzetta EA +2 more
europepmc +1 more source
Detection of Aerosolized Protein Using a Condensation Growth Tube Coupled with an Electrochemical Immunoassay on Screen-Printed Carbon Electrodes. [PDF]
Park J +9 more
europepmc +1 more source
Targeting mitocytosis potentiates mitochondria drug delivery for antimetastasis therapy. [PDF]
Deng Y +5 more
europepmc +1 more source
Tropical volcanism triggers pan-Asian monsoon droughts via circumglobal teleconnection. [PDF]
Nie W, Xia J, Kino K, She D, Oki T.
europepmc +1 more source
Valorizing common pomelo peel by-product via a multi-dimensional framework: a functionally equivalent alternative to a rare botanical for liver health. [PDF]
Liu Y +9 more
europepmc +1 more source
Disruption of afferent neural circuits leads to arrhythmia in the animal model of hereditary sensory and autonomic neuropathy 6. [PDF]
Yoshioka N +9 more
europepmc +1 more source

