Results 31 to 40 of about 363,649 (222)
Tạp chí Khoa học Đại học Cần Thơ, 2023 Nghiên cứu đánh giá ảnh hưởng của nhịp sử dụng vaccine cho ăn và tiềm năng của β-glucan với vitamin C trong tăng cường hiệu quả vaccine phòng bệnh gan thận mủ trên cá tra.
Lê Minh Khôi +3 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Text mining of CHO bioprocess bibliome: Topic modeling and document classification
PLoS ONE, 2023 Chinese hamster ovary (CHO) cells are widely used for mass production of therapeutic proteins in the pharmaceutical industry. With the growing need in optimizing the performance of producer CHO cell lines, research on CHO cell line development and ...
Qinghua Wang +3 more
doaj +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2018 The aim of this study was to test the hypothesis that reduced pre-exercise carbohydrate (CHO) availability potentiates fat oxidation after an exhaustive high-intensity exercise bout. Eight physically active men underwent a high-intensity exercise (∼95% V̇
G.A. Ferreira +6 more
doaj +1 more source
Biological Role of Pazopanib and Sunitinib Aldehyde Derivatives in Drug-Induced Liver Injury
Metabolites, 2022 Tyrosine kinase inhibitors pazopanib and sunitinib are both used to treat advanced renal cell carcinoma but expose patients to an increased risk of hepatotoxicity.
Maud Maillard +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Histamine H1 Receptor Down-Regulation Mediated by M3 Muscarinic Acetylcholine Receptor Subtype
Journal of Pharmacological Sciences, 2004 Heterologous down-regulation of histamine H1 receptor (H1R) mediated by muscarinic acetylcholine receptor subtype was investigated using five kinds of Chinese hamster ovary (CHO) cells stably co-expressing the human H1R and one of the five (M1 –M5 ...
Katsuhiro Miyoshi +5 more
doaj +1 more source
Sử dụng thức ăn viên nuôi cá thát lát còm (Chitala chitala) thương phẩm
Tạp chí Khoa học Đại học Cần Thơ, 2022 Thí nghiệm nuôi cá thát lát còm (Chitala chitala) bằng thức ăn viên nổi được thực hiện trong các giai lưới có diện tích 20 m2/giai với 2 nghiệm thức ăn là thức ăn viên với 4 mức protein (42,5%, 38,6%, 33,6% và 33,2%) và 9% lipid cho 4 giai đoạn nuôi ...
Trần Thị Thanh Hiền +2 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source