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تشخیص مولکولی سرووارهای بیماری زای لپتوسپیرا با روش واکنش زنجیره ای پلیمراز بر اساس ژن lipL21 [PDF]

Archives of Razi Institute, 2015
لپتوسپیروزیس یک بیماری زئونوز با انتشار جهانی است که توسط باکتری لپتوسپیرا اینتروگانس ایجاد می شود. تشخیص دقیق آن برای تمایز لپتوسپیروزیس از دیگر عفونت های تب زا و شایع در محل های مشابه و جهت درمان مناسب حائز اهمیت است.
رسول حسین پور, پژواک خاکی, مجتبی نوفلی, سهیلا مرادی بیدهندی   +3 more
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Exposure and Carriage of Pathogenic Leptospira in Livestock in St. Croix, U.S. Virgin Islands

Tropical Medicine and Infectious Disease, 2021
From 2019–2020, the Virgin Islands Department of Health (VIDOH) investigated potential animal reservoirs of Leptospira spp., the pathogenic bacteria that cause leptospirosis.
Hannah M. Cranford, Marissa Taylor, Andrew Springer Browne, David P. Alt, Tammy Anderson, Camila Hamond, Richard L. Hornsby, Karen LeCount, Linda Schlater, Tod Stuber, Leah De Wilde, Valicia J. Burke-France, Esther M. Ellis, Jarlath E. Nally, Bethany Bradford   +14 more
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Genetic diversity of Leptospira strains circulating in humans and dogs in France in 2019-2021

Frontiers in Cellular and Infection Microbiology, 2023
Leptospirosis is a bacterial zoonotic disease. Humans and dogs are susceptible hosts, with similar clinical manifestations ranging from a febrile phase to multiple organ dysfunction.
Marta Garcia-Lopez, Marta Garcia-Lopez, Celine Lorioux, Anais Soares, Sabine Trombert-Paolantoni, Elena Harran, Florence Ayral, Mathieu Picardeau, Zouheira Djelouadji, Pascale Bourhy   +9 more
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Overcoming problems to produce the recombinant protein LipL21 of Leptospira interrogans

BioTechniques, 2023
The production of leptospiral recombinant proteins in the soluble form and in high yield from Escherichia coli is still a challenge. This work presents the cloning, expression and purification of the outer membrane protein of Leptospira interrogans ...
Maria Beatriz Takahashi, Aline Florencio Teixeira, Ana Lucia Tabet Oller Nascimento   +2 more
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Molecular Detection of Leptospira in Pediatric Aseptic Meningitis

Journal of Microbiology and Infectious Diseases, 2022
Leptospirosis is a zoonotic disease caused by pathogenic Leptospira bacterial species. It is tremendously neglected, and scarce epidemiological data is present worldwide.
Ahmed M. H. Mohamed, Sami E. A. Algam, Abdel Rahim M El Hussein, Isam M Elkhidir, Khalid A Enan   +4 more
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In vivo and in silico Virulence Analysis of Leptospira Species Isolated From Environments and Rodents in Leptospirosis Outbreak Areas in Malaysia

Frontiers in Microbiology, 2021
The zoonotic disease leptospirosis is caused by pathogenic species of the genus Leptospira. With the advancement of studies in leptospirosis, several new species are being reported.
Noraini Philip, Jaeyres Jani, Nurul Natasya Azhari, Zamberi Sekawi, Vasantha Kumari Neela   +4 more
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Activation of Canine, Mouse and Human TLR2 and TLR4 by Inactivated Leptospira Vaccine Strains

Frontiers in Immunology, 2022
Canine Leptospira vaccines contain inactivated strains of pathogenic Leptospira, the causative agents of leptospirosis. For an effective response to vaccination, activation of the innate immune system via pattern recognition receptors such as TLRs is ...
Andreja Novak, Andreja Novak, Elder Pupo, Esther van’t Veld, Victor P. M. G. Rutten, Victor P. M. G. Rutten, Femke Broere, Femke Broere, Arjen Sloots   +8 more
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Bovine endometrial cells do not mount an inflammatory response to Leptospira

Reproduction and Fertility, 2021
Leptospirosis causes abortion, premature birth, and stillbirth in cattle, but the mechanisms remain unclear. Infected cattle shed Leptospira intermittently and present a range of clinical symptoms, making diagnosis difficult.
Paula C C Molinari, Jarlath E Nally, John J Bromfield   +2 more
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Analyzying the documented results by using microscopic agglutination test to examine sera from patients suspected of leptospirosis

Инфекция и иммунитет, 2022
Leptospirosis holds one of the leading places among zoonoses due to the breadth of distribution of natural and economic foci, as well as the severity of the clinical manifestation and mortality rate.
A. P. Samsonova, E. M. Petrov, O. V. Savelyeva, A. E. Ivanova, N. E. Sharapova   +4 more
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THE OUTER MEMBRANE OF PATHOGENIC REPRESENTATIVES OF THE LEPTOSPIRA GENIUS

Инфекция и иммунитет, 2014
. Pathogenic leptospires can infect wide spectrum of hosts and they can survive in the environment long time. The outer membrane is the cellular component participated in interaction of microorganisms and environment.
A. N. Vaganova
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