Results 11 to 20 of about 34,036 (179)

Novel Target for Pathogenic Leptospira Detection via Colorimetric Loop‐Mediated Isothermal Amplification (LAMP): Development, Validation, and Comparative Analysis [PDF]

Journal of Clinical Laboratory Analysis, EarlyView.
A novel colorimetric LAMP assay targeting the org‐hp gene was developed for rapid Leptospira detection. The assay is performed in a simple water bath at 65°C for 90 min, and results can be interpreted by a color change visible to the naked eye. This method provides a sensitive, specific, and field‐adaptable diagnostic tool for use in resource‐limited ...
Peyman Ghoraishizadeh, Benjie Clemente, Kween Saimuang, Sakaorat Lertjuthaporn, Sukhonta limsampan, Patcharapan Suwannin, Mongkol Techakasikornpanich, Galayanee Doungchawee, Edilberto Manahan, Kulachart Jangpatarapongsa   +9 more
wiley   +2 more sources

In Vivo and in Silico Virulence Analysis of Leptospira Species Isolated From Environments and Rodents in Leptospirosis Outbreak Areas in Malaysia

Frontiers in Microbiology, 2021
The zoonotic disease leptospirosis is caused by pathogenic species of the genus Leptospira. With the advancement of studies in leptospirosis, several new species are being reported.
Jaeyres Jani, Vasanthakumari Neela, Zamberi Sekawi   +2 more
exaly   +3 more sources

Eco‐Epidemiological Study of Seropositivity Against Rickettsia and Leptospira Agents in Rural Areas of Urabá, Colombia [PDF]

Tropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Rickettsioses and leptospirosis are infectious diseases often underdiagnosed due to limited knowledge about their epidemiology, pathophysiology, and clinical aspects. Objectives To characterize the seroprevalence and seroincidence of Rickettsia and Leptospira agents and determine their associated factors in rural areas of Urabá ...
Mariana Torres‐Bustamante, Omar Cantillo‐Barraza, Albert I. Ko, Elsio A. Wunder Jr, Juan C. Quintero‐Vélez   +4 more
wiley   +2 more sources

Exposure and Carriage of Pathogenic Leptospira in Livestock in St. Croix, U.S. Virgin Islands

Tropical Medicine and Infectious Disease, 2021
From 2019–2020, the Virgin Islands Department of Health (VIDOH) investigated potential animal reservoirs of Leptospira spp., the pathogenic bacteria that cause leptospirosis.
Hannah M. Cranford, Marissa Taylor, Andrew Springer Browne, David P. Alt, Tammy Anderson, Camila Hamond, Richard L. Hornsby, Karen LeCount, Linda Schlater, Tod Stuber, Leah De Wilde, Valicia J. Burke-France, Esther M. Ellis, Jarlath E. Nally, Bethany Bradford   +14 more
doaj   +1 more source

تشخیص مولکولی سرووارهای بیماری زای لپتوسپیرا با روش واکنش زنجیره ای پلیمراز بر اساس ژن lipL21 [PDF]

Archives of Razi Institute, 2015
لپتوسپیروزیس یک بیماری زئونوز با انتشار جهانی است که توسط باکتری لپتوسپیرا اینتروگانس ایجاد می شود. تشخیص دقیق آن برای تمایز لپتوسپیروزیس از دیگر عفونت های تب زا و شایع در محل های مشابه و جهت درمان مناسب حائز اهمیت است.
رسول حسین پور, پژواک خاکی, مجتبی نوفلی, سهیلا مرادی بیدهندی   +3 more
doaj   +1 more source

Genetic diversity of Leptospira strains circulating in humans and dogs in France in 2019-2021

Frontiers in Cellular and Infection Microbiology, 2023
Leptospirosis is a bacterial zoonotic disease. Humans and dogs are susceptible hosts, with similar clinical manifestations ranging from a febrile phase to multiple organ dysfunction.
Marta Garcia-Lopez, Marta Garcia-Lopez, Celine Lorioux, Anais Soares, Sabine Trombert-Paolantoni, Elena Harran, Florence Ayral, Mathieu Picardeau, Zouheira Djelouadji, Pascale Bourhy   +9 more
doaj   +1 more source

Leptospira dzianensis and Leptospira putramalaysiae are later heterotypic synonyms of Leptospira yasudae and Leptospira stimsonii

, 2021
Leptospira dzianensis and Leptospira putramalaysiae were recently described as novel species and published almost concurrently with Leptospira yasudae and Leptospira stimsonii.
Vincent, Antony T., Bourhy, Pascale, Veyrier, Frederic J., Vasantha Kumari Neela, ., Picardeau, Mathieu, Casanovas-Massana, Arnau   +5 more
core   +2 more sources

Overcoming problems to produce the recombinant protein LipL21 of Leptospira interrogans

BioTechniques, 2023
The production of leptospiral recombinant proteins in the soluble form and in high yield from Escherichia coli is still a challenge. This work presents the cloning, expression and purification of the outer membrane protein of Leptospira interrogans ...
Maria Beatriz Takahashi, Aline Florencio Teixeira, Ana Lucia Tabet Oller Nascimento   +2 more
doaj   +1 more source

Seroprevalence and Clinicoepidemiological Profile of Leptospirosis in Acute Febrile Illness Cases at a Medical College in Amritsar, Punjab, India [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Leptospirosis is an anthropozoonotic disease; it occurs worldwide but is most common in tropical and subtropical countries. It is usually underreported due to a lack of awareness, atypical presentations and lack of diagnostic facilities ...
Prabhjot Kaur, Kanwardeep Singh, Loveena Oberoi, Shailpreet Kaur Sidhu, Amandeep Singh   +4 more
doaj   +1 more source

Molecular Detection of Leptospira in Pediatric Aseptic Meningitis

Journal of Microbiology and Infectious Diseases, 2022
Leptospirosis is a zoonotic disease caused by pathogenic Leptospira bacterial species. It is tremendously neglected, and scarce epidemiological data is present worldwide.
Ahmed M. H. Mohamed, Sami E. A. Algam, Abdel Rahim M El Hussein, Isam M Elkhidir, Khalid A Enan   +4 more
doaj   +1 more source