PLoS Neglected Tropical Diseases, 2020 BACKGROUND:Leptospirosis, commonly known as rat-urine disease, is a global but endemic zoonotic disease in the tropics. Despite the historical report of leptospirosis in Malaysia, the information on human-infecting species is limited.
Noraini Philip +2 more
exaly +2 more sources
Transcriptional Responses of Leptospira interrogans to Host Innate Immunity: Significant Changes in Metabolism, Oxygen Tolerance, and Outer Membrane [PDF]
PLoS Neglected Tropical Diseases, 2010 BACKGROUND: Leptospira interrogans is the major causative agent of leptospirosis. Phagocytosis plays important roles in the innate immune responses to L. interrogans infection, and L. interrogans can evade the killing of phagocytes.
Feng Xue, Jinyu Wu, Zuowei Wu
exaly +2 more sources
cGAS-STING dependent type I IFN reduces Leptospira interrogans renal colonization in mice. [PDF]
PLoS PathogensLeptospira interrogans is the major causative agent of leptospirosis. Humans, canines and agricultural animals are susceptible to Leptospira species and can develop fulminant disease.
Suman Gupta +16 more
doaj +2 more sources
Serovar-specific genomic features of Leptospira interrogans Hardjo: implications for host adaptation [PDF]
Frontiers in Molecular BiosciencesIntroductionLeptospirosis, caused by Leptospira spp., is one of the most widespread zoonoses worldwide. It affects both domestic and wild animals, with ruminants serving as a primary reservoir for serovar Hardjo.
Klaudia Dubniewicz +5 more
doaj +2 more sources
A Dominant Clone of Leptospira interrogans Associated with an Outbreak of Human Leptospirosis in Thailand [PDF]
PLoS Neglected Tropical Diseases, 2007 A sustained outbreak of leptospirosis occurred in northeast Thailand between 1999 and 2003, the basis for which was unknown.A prospective study was conducted between 2000 and 2005 to identify patients with leptospirosis presenting to Udon Thani Hospital ...
Janjira Thaipadungpanit +2 more
exaly +2 more sources
PLoS Neglected Tropical Diseases, 2014 BackgroundLeptospira (L.) interrogans are bacteria responsible for a worldwide reemerging zoonosis. Rodents carry L. interrogans asymptomatically in their kidneys and excrete bacteria in the urine, contaminating the environment.
Martine Fanton D’Andon +2 more
exaly +3 more sources
A Highly Stable Plastidic-Type Ferredoxin-NADP(H) Reductase in the Pathogenic Bacterium Leptospira interrogans [PDF]
PLoS ONE, 2011 Leptospira interrogans is a bacterium that is capable of infecting animals and humans, and its infection causes leptospirosis with a range of symptoms from flu-like to severe illness and death.
Daniela L Catalano-Dupuy +1 more
exaly +2 more sources
Ketone body oxidation and susceptibility to ethyl acetoacetate in a novel hemolytic multidrug-resistant strain Leptospira interrogans KeTo originated from sewage water [PDF]
Scientific ReportsTerrestrial and aquatic environments contaminated with animal urine may contribute to the transmission of Leptospira, a causative agent of leptospirosis in humans and wild/domesticated animals.
Amin Sonam +5 more
doaj +2 more sources
Heliyon, 2021 Leptospirosis is a neglected disease of zoonotic importance and rodents have a known role in epidemiology of Leptospira globally. Paucity of information on the prevalence of leptospirosis in wild rats used as games in Zaria, Nigeria informed the study ...
Collins Chimezie Udechukwu +4 more
doaj +1 more source
Data in Brief, 2021 The data provided in this article is the genomic sequence of new Leptospira isolate, Leptospira interrogans strain HP358 (L. interrogans HP358) isolated from rodent, Sundamys muelleri (S.
Noraini Philip +4 more
doaj +1 more source