Results 1 to 10 of about 877 (84)

Leptospira interrogans and Leptospira kirschneri are the dominant Leptospira species causing human leptospirosis in Central Malaysia

PLoS Neglected Tropical Diseases, 2020
BACKGROUND:Leptospirosis, commonly known as rat-urine disease, is a global but endemic zoonotic disease in the tropics. Despite the historical report of leptospirosis in Malaysia, the information on human-infecting species is limited.
Siti Norbaya Masri, Cyrille Goarant, Yazli Yuhana   +2 more
exaly   +2 more sources

Transcriptional Responses of Leptospira interrogans to Host Innate Immunity: Significant Changes in Metabolism, Oxygen Tolerance, and Outer Membrane [PDF]

PLoS Neglected Tropical Diseases, 2010
BACKGROUND: Leptospira interrogans is the major causative agent of leptospirosis. Phagocytosis plays important roles in the innate immune responses to L. interrogans infection, and L. interrogans can evade the killing of phagocytes.
Jinyu Wu, Bryan Troxell, Feng Xue
exaly   +2 more sources

A Dominant Clone of Leptospira interrogans Associated with an Outbreak of Human Leptospirosis in Thailand [PDF]

PLoS Neglected Tropical Diseases, 2007
A sustained outbreak of leptospirosis occurred in northeast Thailand between 1999 and 2003, the basis for which was unknown.A prospective study was conducted between 2000 and 2005 to identify patients with leptospirosis presenting to Udon Thani Hospital ...
Sharon Peacock, Nicholas John White, Janjira Thaipadungpanit   +2 more
exaly   +2 more sources

Leptospira Interrogans Induces Fibrosis in the Mouse Kidney through Inos-Dependent, TLR- and NLR-Independent Signaling Pathways

PLoS Neglected Tropical Diseases, 2014
BackgroundLeptospira (L.) interrogans are bacteria responsible for a worldwide reemerging zoonosis. Rodents carry L. interrogans asymptomatically in their kidneys and excrete bacteria in the urine, contaminating the environment.
Ivo G Boneca, Martine Fanton d'Andon, Gwenn Ratet   +2 more
exaly   +3 more sources

A Highly Stable Plastidic-Type Ferredoxin-NADP(H) Reductase in the Pathogenic Bacterium Leptospira interrogans [PDF]

PLoS ONE, 2011
Leptospira interrogans is a bacterium that is capable of infecting animals and humans, and its infection causes leptospirosis with a range of symptoms from flu-like to severe illness and death.
Eduardo A. Ceccarelli, Daniela L. Catalano-Dupuy   +1 more
exaly   +2 more sources

Prevalence of Leptospira interrogans in wild rats (Rattus norvegicus and Cricetomys gambianus) in Zaria, Nigeria

Heliyon, 2021
Leptospirosis is a neglected disease of zoonotic importance and rodents have a known role in epidemiology of Leptospira globally. Paucity of information on the prevalence of leptospirosis in wild rats used as games in Zaria, Nigeria informed the study ...
Collins Chimezie Udechukwu, Caleb Ayuba Kudi, Paul Ayuba Abdu, Elmina Abiba Abiayi, Ochuko Orakpoghenor   +4 more
doaj   +1 more source

Effects of Diazinon Exposure on Urinary Shedding of Leptospira interrogans Serogroup Hebdomadis in Mice

Toxics, 2023
Wild rodents are natural hosts of Leptospira spp. and are exposed to various pesticides, some of which are immunotoxic. Rodent urine is an important source of infection for humans and other animals.
So Shinya, Devinda S. Muthusinghe, Nobuo Koizumi, Kumiko Yoshimatsu, Shouta M. M. Nakayama, Mayumi Ishizuka, Yoshinori Ikenaka   +6 more
doaj   +1 more source

Genomic data of Leptospira interrogans HP358 isolated from rodent captured from the human leptospirosis suspected areas of Selangor state, Malaysia

Data in Brief, 2021
The data provided in this article is the genomic sequence of new Leptospira isolate, Leptospira interrogans strain HP358 (L. interrogans HP358) isolated from rodent, Sundamys muelleri (S.
Noraini Philip, Jaeyres Jani, Nurul Natasya Azhari, Zamberi Sekawi, Vasantha Kumari Neela   +4 more
doaj   +1 more source

Leptospirosis is an invasive infectious and systemic inflammatory disease

Biomedical Journal, 2020
Pathogenic Leptospira species are the causative agents of leptospirosis, a world-spreading zoonotic infectious disease. The pathogens possess a powerful invasiveness by invading human body through mucosal/skin barriers, rapid entry into bloodstream to ...
Ai-Hua Sun, Xiao-Xiang Liu, Jie Yan
doaj   +1 more source

A Canine Leptospirosis Clinical Case Due to Leptospira interrogans (Serogroup Icterohaemorrhagiae) in a Dog Kennel in Castelvetrano (Western Sicily, South Italy)

Veterinary Sciences, 2023
Leptospirosis is a worldwide widespread zoonosis caused by Leptospira genus. We report an acute leptospirosis case in a puppy housed at a municipal kennel and the subsequent diagnostic investigations carried out on all dogs housed in the kennel ...
Francesca Grippi, Valeria Blanda, Paola Galluzzo, Manuel Bongiorno, Carmela Sciacca, Francesca Arcuri, Rosalia D’Agostino, Ilenia Giacchino, Francesca Gucciardi, Mario D’Incau, Cristina Bertasio, Alessandra Torina, Annalisa Guercio   +12 more
doaj   +1 more source