Results 41 to 50 of about 36,750 (156)

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

open access: yesAdvanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim   +6 more
wiley   +1 more source

Developing a Single‐Cell Spatial Transcriptomics Workflow for In Vivo Evaluation of Implanted Biomaterials

open access: yesAdvanced Science, EarlyView.
This work establishes a standardized, high‐resolution spatial transcriptomics workflow for characterizing host responses to biomaterial implants. Using the 10× Xenium platform, the pipeline integrates spatial mapping, subclustering, and functional enrichment to resolve immune and stromal cell organization at single‐cell resolution, enabling ...
Alex H.P. Chan   +7 more
wiley   +1 more source

KECERDASAN EMOSIONAL TOKOH TOTTO CHAN DALAM NOVEL MADOGIWA NO TOTTO CHAN KARYA TETSUKO KUROYANAGI MENURUT TEORI GOLEMAN SEBUAH ANALISIS PSIKOLOGI

open access: yesLite: Jurnal Bahasa, Sastra, dan Budaya, 2020
This research is a descriptive psychological analysis study according to Goleman's theory of the emotional intelligence of Totto Chan in the novel Madogiwa no Totto chan by Tetsuko Kuroyanagi.
Noor Laili Faizah, Sri Oemiati
doaj   +1 more source

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li   +22 more
wiley   +1 more source

Chan-Vese Segmentation

open access: yesImage Processing On Line, 2012
While many segmentation methods rely heavily in some way on edge detection, the "Active Contours Without Edges" method by Chan and Vese ignores edges completely.
Pascal Getreuer
doaj   +1 more source

Tunable Switching Mechanisms in HfZrO2‐Based Tunnel Junctions for High‐Performance Synaptic Arrays

open access: yesAdvanced Science, EarlyView.
This work demonstrates hybrid switching in engineered HZO‐based FTJs, enabled by controlled interlayer design and oxygen scavenging dynamics. The combined switching mechanism produces robust multilevel conductance states in large crossbar arrays, offering a materials‐driven pathway toward scalable in‐memory computing with enhanced tunability and ...
Jiwon You   +8 more
wiley   +1 more source

HIỆU QUẢ CHĂN NUÔI VỊT ĐẺ CHẠY ĐỒNG Ở ĐBSCL

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2008
Đề tài nghiên cứu nhằm phân tích hiệu quả chăn nuôi và các yếu tố ảnh hưởng đến hiệu quả chăn nuôi vịt lấy trứng theo phương thức chạy đồng ở Đồng bằng sông Cửu Long.
Mai Văn Nam
doaj  

Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era

open access: yesAdvanced Science, EarlyView.
This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley   +1 more source

Metabologenomic Hallmark‐Based Discovery of Bacterial Thioamides as a New Lead against Drug‐Resistant Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
A targeted metabologenomic strategy integrating genomic and metabolomic hallmarks enabled the discovery of two new thioamides, thiogochangamides A and B, from bacteria. Their absolute configurations, previously unresolved within the thioviridamide family, were fully assigned through various chemical derivatizations and computational analysis ...
Young Eun Du   +18 more
wiley   +1 more source

Nierozróżniający wgląd w medytacji buddyzmu chan i jego wczesnobuddyjskie analogie

open access: yesArgument, 2017
Undifferentiating insight in the Chan Buddhist meditation and its early Buddhist analogies: In the paper a comparative analysis of Chan Buddhist meditation and the early Buddhist meditation has been conducted.
Kamil NOWAK
doaj   +1 more source

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