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Humoral immune responses to ChAdOx1 nCoV-19 in children

COVID-19 vaccination of children and young people is recommended in some countries. Data on immune responses induced by COVID-19 vaccines in children have been reported less widely than for adults. COV006 was a phase II, single-blind, randomised controlled trial of ChAdOx1 nCoV-19 in healthy participants 6-17 years of age.
Li, Grace
openaire   +3 more sources

Steven Johnson Syndrome Following ChAdOx1 nCoV-19 Vaccination (AstraZeneca) [PDF]

Annals of Dermatology, 2023
Hyo Jin Lee, So Yeon Yun, Jin Young Choi, Young Bok Lee   +3 more
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Kinetics of the Antibody Response to Boostering With Three Different Vaccines Against SARS-CoV-2

Frontiers in Immunology, 2022
BackgroundHeterologous vaccinations against SARS-CoV-2 with ChAdOx1 nCoV-19 and a second dose of an mRNA-based vaccine have been shown to be more immunogenic than homologous ChAdOx1 nCoV-19.
Robert Markewitz, David Juhl, Daniela Pauli, Siegfried Görg, Ralf Junker, Jan Rupp, Sarah Engel, Katja Steinhagen, Victor Herbst, Dorinja Zapf, Christina Krüger, Christian Brockmann, Frank Leypoldt, Justina Dargvainiene, Benjamin Schomburg, Shahpour Sharifzadeh, Lukas Salek Nejad, Klaus-Peter Wandinger, Malte Ziemann   +18 more
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Cerebral venous thrombosis due to vaccine-induced immune thrombotic thrombocytopenia after a second ChAdOx1 nCoV-19 dose [PDF]

, 2022
© 2022 by The American Society of Hematology. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0), permitting only noncommercial, nonderivative use with attribution.
Heldner, Mirjam R., Arnold, Marcel, Ferro, José M., de Sousa, Diana Aguiar, Zimmermann, Julian, Pötzsch, Bernd, Frisullo, Giovanni, Karapanayiotides, Theodoros, Aguiar de Sousa, Diana, Kremer Hovinga, Johanna A., Ferro, José, van de Munckhof, Anita, Bode, Felix J., Coutinho, Jonathan M., Zimmerman, Julian, Bode, Felix J, Coutinho, Jonathan M, Kremer Hovinga, Johanna Anna, Ferro, Jose M, Krzywicka, Katarzyna, Sánchez van Kammen, Mayte   +20 more
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Takotsubo (stress) cardiomyopathy after ChAdOx1 nCoV-19 vaccination [PDF]

BMJ Case Reports, 2021
The global COVID-19 pandemic remains challenging with efforts for community vaccination the primary strategy to control transmission and disease sequalae in the mid to long term. While several candidate vaccines have been approved for use, there is an ongoing discussion regarding potential vaccine-related adverse events.
Phillip Crane, Chiew Wong, Nilesh Mehta, Peter Barlis   +3 more
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ChAdOx1 nCoV-19 (AZD1222) vaccine candidate significantly reduces SARS-CoV-2 shedding in ferrets

npj Vaccines, 2021
Vaccines against SARS-CoV-2 are likely to be critical in the management of the ongoing pandemic. A number of candidates are in Phase III human clinical trials, including ChAdOx1 nCoV-19 (AZD1222), a replication-deficient chimpanzee adenovirus-vectored ...
Glenn A. Marsh, Alexander J. McAuley, Gough G. Au, Sarah Riddell, Daniel Layton, Nagendrakumar B. Singanallur, Rachel Layton, Jean Payne, Peter A. Durr, Hannah Bender, Jennifer A. Barr, John Bingham, Victoria Boyd, Sheree Brown, Matthew P. Bruce, Kathie Burkett, Teresa Eastwood, Sarah Edwards, Tamara Gough, Kim Halpin, Jenni Harper, Clare Holmes, William S. J. Horman, Petrus Jansen van Vuren, Suzanne Lowther, Kate Maynard, Kristen D. McAuley, Matthew J. Neave, Timothy Poole, Christina Rootes, Brenton Rowe, Elisha Soldani, Vittoria Stevens, Cameron R. Stewart, Willy W. Suen, Mary Tachedjian, Shawn Todd, Lee Trinidad, Duane Walter, Naomi Watson, Trevor W. Drew, Sarah C. Gilbert, Teresa Lambe, S. S. Vasan   +43 more
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Quadriparesis with different diagnoses after COVID-19 vaccination: Case series and literature review

Journal of Family Medicine and Primary Care, 2023
Following vaccination with adenoviral vector-based ChAdOx1 nCoV-19, serious neurological adverse events have been reported. Here we report two cases who presented with quadriparesis following the adenoviral vector-based ChAdOx1 nCoV-19 vaccine. A 55-year-
Sachin Wali, Shreyas Gutte, Shubham Yadav, Mohan Gurjar, Vimal K. Paliwal, Vivek Singh, Afzal Azim, Banani Poddar   +7 more
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Comparative analysis of ChAdOx1 nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines: [Preprint] [PDF]

, 2021
Vector-based SARS-CoV-2 vaccines have been associated with vaccine-induced thrombosis with thrombocytopenia syndrome (VITT/TTS), but the causative factors are still unresolved.
Cammann, Clemens, Greinacher, Andreas, Schindler, Maximilian, Wesche, Jan, Hentschker, Christian, Franzke, Kati, Endlich, Nicole, Reder, Alexander, Palankar, Raghavendra, Siegerist, Florian, Steil, Leif, Gesell-Salazar, Manuela, Beer, Martin, Michalik, Stephan, Seifert, Ulrike, Völker, Uwe, Reisinger, Emil   +16 more
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Tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine: An open-label partially-randomised ascending dose phase I trial

EBioMedicine, 2022
Summary: Background: Intranasal vaccination may induce protective local and systemic immune responses against respiratory pathogens. A number of intranasal SARS-CoV-2 vaccine candidates have achieved protection in pre-clinical challenge models ...
Meera Madhavan, Adam J. Ritchie, Jeremy Aboagye, Daniel Jenkin, Samuel Provstgaad-Morys, Iona Tarbet, Danielle Woods, Sophie Davies, Megan Baker, Abigail Platt, Amy Flaxman, Holly Smith, Sandra Belij-Rammerstorfer, Deidre Wilkins, Elizabeth J. Kelly, Tonya Villafana, Justin A. Green, Ian Poulton, Teresa Lambe, Adrian V.S. Hill, Katie J. Ewer, Alexander D. Douglas   +21 more
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Digital PCR to quantify ChAdOx1 nCoV-19 copies in blood and tissues

Molecular Therapy: Methods & Clinical Development, 2021
Vaccination with the adenoviral-vector-based AstraZeneca ChAdOx1 nCov-19 (Vaxzevria) vaccine is efficient and safe. However, in rare cases vaccinated individuals developed life-threatening thrombotic complications, including thrombosis in cerebral sinus ...
Anita Badbaran, Reiner K. Mailer, Christine Dahlke, Jannis Woens, Anahita Fathi, Sibylle C. Mellinghoff, Thomas Renné, Marylyn M. Addo, Kristoffer Riecken, Boris Fehse   +9 more
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