Results 101 to 110 of about 111,359 (301)

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

Nature, 2016
Chagas disease, leishmaniasis and sleeping sickness affect 20 million people worldwide and lead to more than 50,000 deaths annually. The diseases are caused by infection with the kinetoplastid parasites Trypanosoma cruzi, Leishmania spp.
Shilpi Khare, A. Nagle, Agnes Biggart, Yin H. Lai, Fang-Ping Liang, Lauren C. Davis, S. W. Barnes, Casey J. N. Mathison, E. Myburgh, E. Myburgh, Mu-Yun Gao, J. R. Gillespie, Xianzhong Liu, J. Tan, Monique Stinson, Ianne Rivera, Jaime Ballard, V. Yeh, T. Groessl, Glenn C. Federe, Hazel X. Y. Koh, John D. Venable, B. Bursulaya, Michael Shapiro, Mishra Pranab, G. Spraggon, Ansgar Brock, J. Mottram, J. Mottram, F. Buckner, Srinivasa P. S. Rao, Ben G. Wen, J. Walker, T. Tuntland, V. Molteni, R. Glynne, F. Supek   +36 more
semanticscholar   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

Estimating the current burden of Chagas disease in Mexico: A systematic review and meta-analysis of epidemiological surveys from 2006 to 2017

PLoS Neglected Tropical Diseases, 2019
Background In Mexico, estimates of Chagas disease prevalence and burden vary widely. Updating surveillance data is therefore an important priority to ensure that Chagas disease does not remain a barrier to the development of Mexico's most vulnerable ...
A. Arnal, E. Waleckx, O. Rico‐Chávez, Claudia P Herrera, Eric Dumonteil   +4 more
semanticscholar   +1 more source

The history of Chagas disease [PDF]

Parasites & Vectors, 2014
The ancestor of Trypanosome cruzi was probably introduced to South American via bats approximately 7-10 million years ago. When the first humans arrived in the New World, a sylvatic cycle of Chagas disease was then already well established. Paleoparasitological data suggests that human American trypanosomiasis originated in the Andean area when people ...
openaire   +5 more sources

Ultrasound‐assisted recirculation extraction as an innovative approach for obtaining bioactive compounds from grape pomace

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Grape pomace, a by‐product generated during winemaking, still retains bioactive compounds with potential applications in the food, pharmaceutical and nutraceutical sectors. This work investigated ultrasound‐assisted extraction (UAE) coupled with a recirculation system as a strategy to improve their recovery.
Jailton Ribeiro Dos Santos Junior, Luiz Carlos Corrêa‐Filho, Dayvison Mendes Moreira, Renata Valeriano Tonon, Lourdes Maria Correa Cabral   +4 more
wiley   +1 more source

Composition and functionalities of peanut protein concentrates using ethanol as a defatted solvent and a precipitating agent

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Defatted solids (DSs) from vegetable oil extraction represent valuable feedstocks for producing protein concentrates with tailored functional properties. In the present study, using peanut protein concentrates obtained from press cakes defatted with ethanol (DSEt) or hexane (DSHx), we aimed to evaluate ethanol as a green solvent for
Paloma Jamily Cristina Magalhães, Luiza Cardoso Stumm, Paola de Cássia Franco Visioli, Keila Kazue Aracava, Rafaela Torrezan Privatti, Maria Carolina Capellini, Silvana Marina Piccoli Pugine, Daniel Gonçalves, Christianne Elisabete da Costa Rodrigues   +8 more
wiley   +1 more source

MOLECULAR DETECTION OF ENTEROVIRUS D68 IN CASES OF ACUTE RESPIRATORY INFECTION OCCURRING IN THE STATE OF ACRE

Brazilian Journal of Infectious Diseases
Introduction/Objectives: Enterovirus D68 (EV-D68) is an emerging virus of the Enterovirus genus, mainly associated with acute respiratory infections (ARI) and, less frequently, with neurological manifestations such as acute flaccid myelitis.
Ana Luiza da Mota Raminho, Wanderley Dias das Chagas Junior, Daniele Ferreira Bezerra, Karla Fabiane Lopes de Melo, Amanda Mendes Silva Cruz, Luana Soares Barbagelata, Agatha Monike Silva Nunes, Maria Silvia Sousa de Lucena, Josilene Félix da Rocha, James Ferreira Lima, Mirleide Cordeiro dos Santos, Fernando Neto Tavares   +11 more
doaj   +1 more source

The presence of antibodies for hepatitis a virus in amazonia Didelphis marsupialis (Vertebrata, Marsupialia)

Revista do Instituto de Medicina Tropical de São Paulo, 1987
Anti-HAV was detected by enzyme - immunoassay in sera collected from 6 (18,75%) of 32 Didelphis marsupialis trapped in the Amazon region. No anti-HAV were found in the sera from 136 other wild animals, including small rodents, reptiles and other ...
Manoel do Carmo P. Soares, Gilberta Bensabath, Amélia P. A. Travassos da Rosa   +2 more
doaj   +1 more source

Chagas Disease

Neglected Tropical Diseases, 2021
Paula E. Stigler Granados, Colin Forsyth
semanticscholar   +1 more source