Results 141 to 150 of about 114,131 (308)

Chagas disease pharmacotherapy and its chemical structure activity relationship

open access: yes, 2017
Therapeutic arsenal currently available for Chagas disease is restricted in only two drugs, nifurtimox and benznidazole, since 1960s and 1970s, respectively. Despite the efforts to develop new drugs, until now, no new drugs were approved.
Scarim, Cauê Benito [UNESP]   +4 more
core  

Characterization of a Portable Computed Tomography System for In Situ Analysis of Wooden Sculptures in Cultural Heritage

open access: yesX-Ray Spectrometry, EarlyView.
ABSTRACT Portable X‐ray computed tomography (portable CT) has become an important tool for the non‐destructive investigation of cultural heritage objects, particularly when in situ analysis is required. This work presents the experimental characterization and application of a transportable cone‐beam CT system designed for the inspection of large and ...
Anderson de Paula   +7 more
wiley   +1 more source

Alterações clínicolaboratoriais em pacientes com malária por Plasmodium vivax e deficiência de glicose-6-fosfato desidrogenase tratados com 0,50mg/kg/dia de primaquina

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2004
O efeito adverso da primaquina na dose de 0,50mg/kg/dia foi investigado em onze pacientes com malária vivax (três com deficiência de glicose-6-fosfato desidrogenase).
Mônica C.M. Silva   +5 more
doaj  

Chagas disease : neglected parasitic infections in the United States [PDF]

open access: yes
Chagas disease is a preventable infection caused by the parasite Trypanosoma cruzi and spread by infected insects called triatomine bugs, also known as \u201ckissing bugs.\u201d The initial infection usually does not cause severe symptoms and is often ...

core  

Multielemental Analysis in Rice Grains by Total Reflection X‐Ray Fluorescence

open access: yesX-Ray Spectrometry, EarlyView.
ABSTRACT Rice (Oryza sativa) is a staple food cultivated worldwide and represents a significant source of essential nutrients for humans. However, this cereal may also contain potentially toxic elements including chromium, arsenic, and lead typically present at trace concentrations (ng.g−1).
F. T. S. Tsuyama   +8 more
wiley   +1 more source

Calcitonin‐like diuretic hormone influences reproduction in adult female Rhodnius prolixus

open access: yesInsect Science, EarlyView.
Highlights • CT/DH‐like immunoreactivity is present in female reproductive tissues • CT/DH receptor transcripts are expressed in the fat body and ovaries • RNAi knockdown of CT/DH receptors reduces egg number and hatching rate • Rhopr‐CT/DH increases RhoprVg1 and RhoprVgR expression in ovaries in vitro • Rhopr‐CT/DH stimulates oviduct contractions in a
Areej N. Al‐Dailami   +2 more
wiley   +1 more source

Chagas Disease: Sharing the Burden and the Solutions in the United States and Mexico

open access: yes, 2015
Chagas disease—the third most common parasitic infection in the world—affects approximately 7.5 million people, mostly in Latin America. Population mobility between Latin America and the rest of the world has led to increasing detection of Chagas disease
Matthews, Kirstin R.W.   +1 more
core  

Evidence of internal structure validity of the nursing outcome “Mechanical Ventilation Weaning Response: Adult (0412)” for critically ill COVID‐19 patients

open access: yesInternational Journal of Nursing Knowledge, EarlyView.
Abstract Purpose To evaluate the evidence of internal structure validity of the nursing outcome (NO) “Mechanical Ventilation Weaning Response: Adult (0412)” of the NOs classification for critically ill COVID‐19 patients. Methods A methodological study focused on internal structural validation, part of a multicenter study, was carried out in the ...
Aline Batista Maurício   +8 more
wiley   +1 more source

Analysis of the Epidemiological Profile of Typhoid Fever in the State of Pará Between the Years 1999 and 2018

open access: yesInternational Journal of Microbiology
Salmonella Typhi is the causative agent of typhoid fever, a notifiable disease characterized by prolonged fever and gastrointestinal symptoms that may worsen and lead to death.
Danielle Vieira Pina de Carvalho   +2 more
doaj   +1 more source

Therapeutic targets in chagas disease

open access: yes, 2017
Optimal pharmacotherapy occurs when we have selectivity and no toxicity. The discovery of specific pathways or enzymes that are vital forcell or parasite survival is also vital for the design of new specific, non-toxic drugs for the treatment of cancer ...
Scarim, Cauê Benito [UNESP]   +4 more
core  

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