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The Lancet, 2018
Chagas disease is an anthropozoonosis from the American continent that has spread from its original boundaries through migration. It is caused by the protozoan Trypanosoma cruzi, which was identified in the first decade of the 20th century. Once acute infection resolves, patients can develop chronic disease, which in up to 30-40% of cases is ...
José A, Pérez-Molina, Israel, Molina
semanticscholar +5 more sources
Chagas disease is an anthropozoonosis from the American continent that has spread from its original boundaries through migration. It is caused by the protozoan Trypanosoma cruzi, which was identified in the first decade of the 20th century. Once acute infection resolves, patients can develop chronic disease, which in up to 30-40% of cases is ...
José A, Pérez-Molina, Israel, Molina
semanticscholar +5 more sources
Chagas Disease: Chronic Chagas Cardiomyopathy
Current Problems in Cardiology, 2021Chagas disease (CD) is a tropical vector-borne infection caused by the protozoan parasite Trypanosoma cruzi (T. cruzi), also known as American Trypanosomiasis. It is considered endemic in all South and Central America and in this past decades its becoming a burden particularly in the United States and Europe due to human migration. The vast majority of
Natalia Giraldo Echavarría +4 more
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Chagas Disease: From Discovery to a Worldwide Health Problem
Frontiers in Public Health, 2019 Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in his honor, just over a century ago. He described the clinical aspects of the disease, characterized by its etiological agent (Trypanosoma cruzi) and identified its ...
Kárita Cláudia Freitas Lidani +2 more
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Chagas Disease in the United States: a Public Health Approach
Clinical Microbiology Reviews, 2019 Trypanosoma cruzi is the etiological agent of Chagas disease, usually transmitted by triatomine vectors. An estimated 20 to 30% of infected individuals develop potentially lethal cardiac or gastrointestinal disease.
Louisa A Messenger, Jeffrey D Whitman
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Circulation, 2018 Background: Chagas disease, resulting from the protozoan Trypanosoma cruzi, is an important cause of heart failure, stroke, arrhythmia, and sudden death. Traditionally regarded as a tropical disease found only in Central America and South America, Chagas
Walderez Dutra +2 more
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Pathology and Pathogenesis of Chagas Heart Disease
Annual Review of Pathology: Mechanisms of Disease, 2019 Chagas heart disease is an inflammatory cardiomyopathy that develops in approximately one-third of people infected with the protozoan parasite Trypanosoma cruzi. One way T.
Nisha J Garg, David M Engman
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The Lancet, 2010
Chagas disease is a chronic, systemic, parasitic infection caused by the protozoan Trypanosoma cruzi, and was discovered in 1909. The disease affects about 8 million people in Latin America, of whom 30-40% either have or will develop cardiomyopathy, digestive megasyndromes, or both.
Anis, Rassi +2 more
openaire +4 more sources
Chagas disease is a chronic, systemic, parasitic infection caused by the protozoan Trypanosoma cruzi, and was discovered in 1909. The disease affects about 8 million people in Latin America, of whom 30-40% either have or will develop cardiomyopathy, digestive megasyndromes, or both.
Anis, Rassi +2 more
openaire +4 more sources
Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy
New England Journal of Medicine, 2015 Alvaro Aa Avezum +2 more
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Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness
Nature, 2016 Chagas disease, leishmaniasis and sleeping sickness affect 20 million people worldwide and lead to more than 50,000 deaths annually. The diseases are caused by infection with the kinetoplastid parasites Trypanosoma cruzi, Leishmania spp.
Casey J N Mathison +2 more
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Dimensions of Critical Care Nursing, 2023
Abstract Chagas disease is a prominent neglected tropical disease endemic to many countries in Latin America. Cardiomyopathy is the most serious manifestation due to the severity and complications of heart failure. As a result of expanded immigration and globalization, there is an increased number of patients with Chagas cardiomyopathy who are being ...
Ariana, Jimenez, Elizabeth J, Winokur
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Abstract Chagas disease is a prominent neglected tropical disease endemic to many countries in Latin America. Cardiomyopathy is the most serious manifestation due to the severity and complications of heart failure. As a result of expanded immigration and globalization, there is an increased number of patients with Chagas cardiomyopathy who are being ...
Ariana, Jimenez, Elizabeth J, Winokur
openaire +2 more sources