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Dimensions of Critical Care Nursing, 2023
Abstract Chagas disease is a prominent neglected tropical disease endemic to many countries in Latin America. Cardiomyopathy is the most serious manifestation due to the severity and complications of heart failure. As a result of expanded immigration and globalization, there is an increased number of patients with Chagas cardiomyopathy who are being ...
Ariana, Jimenez, Elizabeth J, Winokur
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Abstract Chagas disease is a prominent neglected tropical disease endemic to many countries in Latin America. Cardiomyopathy is the most serious manifestation due to the severity and complications of heart failure. As a result of expanded immigration and globalization, there is an increased number of patients with Chagas cardiomyopathy who are being ...
Ariana, Jimenez, Elizabeth J, Winokur
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Chagas Disease: Chronic Chagas Cardiomyopathy
Current Problems in Cardiology, 2021Chagas disease (CD) is a tropical vector-borne infection caused by the protozoan parasite Trypanosoma cruzi (T. cruzi), also known as American Trypanosomiasis. It is considered endemic in all South and Central America and in this past decades its becoming a burden particularly in the United States and Europe due to human migration. The vast majority of
Natalia Giraldo Echavarría +4 more
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Autoantibodies in Chagas' Cardiomyopathy and Arrhythmias
Autoimmunity, 2001 Pablo A Chiale, I Ferrari
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Chagas cardiomyopathy and captopril
European Heart Journal, 1992Chagas disease is a leading cause of heart failure in Latin America. Sudden death occurs in approximately 40% of patients with heart failure due to Chagas disease. We report a single blind, cross-over trial of prolonged treatment with captopril and placebo in 18 Chagas disease patients with class IV NYHA heart failure.
Roberti, Roberto Rinaldo UNIFESP +6 more
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Outcome of Chagas cardiomyopathy in comparison to ischemic cardiomyopathy
International Journal of Cardiology, 2013Chagas cardiomyopathy and ischemic heart disease (IHD) are frequent causes of chronic systolic heart failure (CHF) in areas where the former is endemic. Nonetheless, a specific comparison of outcome and role of etiology of CHF failure has not been performed in patients with both conditions.Two-hundred twenty two patients with Chagas cardiomyopathy and ...
Ana Paula Otaviano +1 more
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Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy
New England Journal of Medicine, 2015 The role of trypanocidal therapy in patients with established Chagas' cardiomyopathy is unproven.We conducted a prospective, multicenter, randomized study involving 2854 patients with Chagas' cardiomyopathy who received benznidazole or placebo for up to 80 days and were followed for a mean of 5.4 years. The primary outcome in the time-to-event analysis
Alvaro Avezum +2 more
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An update on the management of Chagas cardiomyopathy
Expert Review of Anti-infective Therapy, 2007Chagas disease, caused by the protozoan parasite Trypanosoma cruzi, infects nearly 18 million people in Latin America and mainly affects the heart, causing heart failure, arrhythmias, heart block, thromboembolism, stroke and death. In this review, the clinical diagnosis and management of Chagas cardiomyopathy are discussed.
Manoel O C, Rocha +2 more
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Heart transplantation for chagas' cardiomyopathy
The Annals of Thoracic Surgery, 1995We present 2 patients who underwent orthotopic heart transplantation for end-stage Chagas' cardiomyopathy. Despite immunosuppressive therapy, postoperative prophylaxis with nifurtimox appeared to prevent Trypanosoma cruzi reactivation. Neither patient has shown signs of Chagas' myocarditis, and both are clinically well 12 and 72 months after ...
C, Blanche +5 more
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2018
Abstract Chagas’ cardiomyopathy is a major complication emerging from Trypanosoma cruzi infection, appearing in up to 30% of individuals with positive serology and being the principal cause of death from heart failure in some areas of South America.
Carlos Eduardo Rochitte +1 more
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Abstract Chagas’ cardiomyopathy is a major complication emerging from Trypanosoma cruzi infection, appearing in up to 30% of individuals with positive serology and being the principal cause of death from heart failure in some areas of South America.
Carlos Eduardo Rochitte +1 more
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Chagas cardiomyopathy and ischemic stroke
Expert Review of Cardiovascular Therapy, 2006American trypanosomiasis, known as Chagas disease is a major cause of cardiomyopathy in South America. Irreversible damage to the heart can appear 10-20 years after chagasic infection. The relationship between Chagas cardiomyopathy and ischemic stroke has been reviewed.
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