Results 111 to 120 of about 9,204,525 (344)

Clinical and pharmacological profile of benznidazole for treatment of Chagas disease

Expert Review of Clinical Pharmacology, 2018
Introduction: Chagas disease (CD) is one of the most neglected public health problems in the Americas, where
J. Kratz, F. García Bournissen, Colin J. Forsyth, S. Sosa-Estani   +3 more
semanticscholar   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Chagas Disease Serological Test Performance in U.S. Blood Donor Specimens

Journal of Clinical Microbiology, 2019
Chagas disease affects an estimated 300,000 individuals in the United States. Diagnosis in the chronic phase requires positive results from two different IgG serological tests. Three enzyme-linked immunosorbent assays (ELISAs) (Hemagen, Ortho, and Wiener)
Jeffrey D. Whitman, Christina A. Bulman, Emma L Gunderson, A. Irish, Rebecca L. Townsend, S. Stramer, J. Sakanari, C. Bern   +7 more
semanticscholar   +1 more source

Preliminary non‐comparative evaluation of an adapted colonoscopy preparation protocol for dogs using sodium picosulphate and magnesium citrate

Veterinary Record, EarlyView.
Abstract Background Challenges associated with bowel cleansing protocols for canine colonoscopy include practical applicability and inadequate preparations. This study aimed to describe and evaluate an adapted protocol to simplify colonoscopy preparation in dogs.
Julia Elia da Silva Paranhos, Melissa Guillen Gonçalves de Souza, Daniela Araujo de Sousa, Debora Costabile Soibelman, Sabrina Martins da Costa Ferreira, Juliana da Silva Leite, Bruno Penna, Ana Maria Reis Ferreira   +7 more
wiley   +1 more source

Health literacy & Chagas disease knowledge: A cross-sectional study in Southern Loja Province, Ecuador

PEC Innovation
Objective: Health literacy is associated with many patient outcomes. This study sought to determine the association between a person's level of health literacy and their knowledge about Chagas disease. Methods: A cross-sectional survey was conducted with
Talia L. Caridi, Fernanda Mariño-Polo, Cora G. Farra, Alison M. Mingus, Athar Memon, Mario J. Grijalva, Benjamin R. Bates   +6 more
doaj   +1 more source

Mortality Related to Chagas Disease and HIV/AIDS Coinfection in Brazil

Journal of Tropical Medicine, 2012
Chagas disease in patients with HIV infection represents a potentially serious event with high case fatality rates. This study describes epidemiological and clinical aspects of deaths related to Chagas disease and HIV/AIDS coinfection in Brazil, 1999 ...
Francisco Rogerlândio Martins-Melo, Alberto Novaes Ramos, Carlos Henrique Alencar, Jorg Heukelbach   +3 more
doaj   +1 more source

Risks of endemicity, morbidity and perspectives regarding the control of Chagas disease in the Amazon Region

Memorias do Instituto Oswaldo Cruz, 2012
Chagas disease, in the Amazon Region as elsewhere, can be considered an enzootic disease of wild animals or an anthropozoonosis, an accidental disease of humans that is acquired when humans penetrate a wild ecosystem or when wild triatomines invade human
José Rodrigues Coura, Angela CV Junqueira   +1 more
doaj   +1 more source

The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]

, 2005
Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O., Leguizamon, M.S., Mucci, J., Rooijen, N. van, Tribulatti, M.V.   +4 more
core   +2 more sources

Prevalence of Chagas disease in Colombia: A systematic review and meta-analysis

PLoS ONE, 2019
Background Despite the adoption of campaigns to interrupt the main vector and to detect Trypanosoma cruzi in blood banks, millions of people are still chronically infected; however, the prevalence data are limited, and the epidemiology of Chagas disease ...
M. Olivera, J. A. Fory, Julia Porras, G. Buitrago   +3 more
semanticscholar   +1 more source

Evaluation of two candidate molecules—TCTP and cecropin—on the establishment of Trypanosoma brucei gambiense into the gut of Glossina palpalis gambiensis

Insect Science, EarlyView.
This study investigates the potential of enhancing the resistance of Glossina palpalis gambiensis to Trypanosoma brucei gambiense to mitigate the transmission of Human African Trypanosomiasis. We successfully cloned genes encoding proteins of interest in Sodalis strains, resulting in recombinant Sodalis (recSodalis) that were micro‐injected into the L3
François Sougal Ngambia Freitas, Linda De Vooght, Flobert Njiokou, Jan Van Den Abeele, Géraldine Bossard, Bernadette Tchicaya, Rosa Milagros Corrales, Sophie Ravel, Anne Geiger, David Berthier‐Teyssedre   +9 more
wiley   +1 more source