Results 111 to 120 of about 92,352 (267)

'It is like a tomato stall where someone can pick what he likes': structure and practices of female sex work in Kampala, Uganda. [PDF]

, 2013
BACKGROUND: Effective interventions among female sex workers require a thorough knowledge of the context of local sex industries. We explore the organisation of female sex work in a low socio-economic setting in Kampala, Uganda.
A-M Cote, AH Norris, C Harcourt, D Whittaker, F Scorgie, F Van den Borne, G Asiki, I Vanwesenbeeck, IB Zablotska, J Bukenya, J Nazziwa, J Seeley, J Vandepitte, J Vandepitte, JAA Munoz, Janet Seeley, JP Ntozi, Judith Vandepitte, K Fritz, L Van Blerk, M Gysels, M Mbonye, Martin Mbonye, ML Rekart, NTT Thuy, PM Pyett, QA Karim, Rachel King, S Baral, S Jana, Sarah Nakamanya, SC Kalichman, SE Woolf-King, UNAIDS, Winifred Nalukenge   +34 more
core   +2 more sources

Treatment of Chagas disease

, 2010
Abstract Although Chagas disease has existed for at least 9000 years, its treatment is recent: the internationally accepted drugs nifurtimox and benznidazole date from the 1970s. Both drugs are effective in acute cases, in congenital cases, in reactivation of chronic cases, and in new chronic cases. Its usefulness in chronic cases has not been shown,
openaire   +3 more sources

Genetic Reduction of the Translational Repressors FMRP and 4E‐BP2 Preserves Memory in Mouse Models of Alzheimer's Disease

Aging Cell, EarlyView.
Genetic reduction of the translational repressors FMRP or 4E‐BP2 prevents amyloid‐β oligomer–induced suppression of hippocampal protein synthesis and memory loss in mice. Targeting translational control preserves cognitive function in Alzheimer's models, revealing mRNA translation as a promising therapeutic axis for memory preservation.
Felipe C. Ribeiro, Danielle Cozachenco, Michael Parkhill, Brandon Rodrigue, Caio Borges, Jean‐Claude Lacaille, Karim Nader, Fernanda G. De Felice, Mychael V. Lourenco, Argel Aguilar‐Valles, Nahum Sonenberg, Sergio T. Ferreira   +11 more
wiley   +1 more source

Natural selection and genetic variation in a promising Chagas disease drug target: Trypanosoma cruzi trans-sialidase [PDF]

, 2017
Rational drug design is a powerful method in which new and innovative therapeutics can be designed based on knowledge of the biological target aiming to provide more efficacious and responsible therapeutics.
Gallant, Joseph P.
core   +1 more source

Mapping Dental Care for Children and Adolescents With Rare Diseases: A Brazilian Multicentre Study

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Objectives To describe the landscape of dental care provided by specialised centres for children and adolescents with rare diseases (RDs) in the state of Minas Gerais, southeastern Brazil. Methods A retrospective cross‐sectional study was conducted involving individuals aged 0–18 years with a confirmed diagnosis of a RD who received care at ...
Heloisa Vieira Prado, Rayssa Maria Soalheiro de Souza, Gabriella Guerra Freire Gabrich Fonseca, Kamila Rodrigues Junqueira Carvalho, Anna Vitória Mendes Viana Silva, Iasmin Fonseca Tolentino Mascarenhas, Beatriz Rezende Bergo, Hanna Larissa Barbosa Soares, Bárbara Mendes de Jesus, Layanne Ribeiro Ferreira e Sobral, Kélisson Duarte Reis, Késia Lara dos Santos Marques, Fabiana Sodré de Oliveira, Daniella Reis Barbosa Martelli, José Alcides Almeida de Arruda, Benjamin P. J. Fournier, Denise Vieira Travassos, Soraia Macari, Célia Regina Moreira Lanza, Ana Cristina Borges‐Oliveira, Hercílio Martelli‐Júnior, Tarcília Aparecida Silva   +21 more
wiley   +1 more source

Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) trial

Memorias do Instituto Oswaldo Cruz
Chagas cardiomyopathy is the most frequent and most severe manifestation of chronic Chagas disease, and is one of the leading causes of morbidity and death in Latin America.
Anis Rassi Jr, José Antonio Marin Neto, Anis Rassi   +2 more
doaj   +1 more source

Discrete typing units of Trypanosoma cruzi identified in rural dogs and cats in the humid Argentinean Chaco [PDF]

, 2012
The discrete typing units (DTUs) of Trypanosoma cruzi that infect domestic dogs and cats have rarely been studied. With this purpose we conducted a cross-sectional xenodiagnostic survey of dog and cat populations residing in 2 infested rural villages in ...
Cardinal, Marta Victoria, Enriquez, Gustavo Fabián, Gurtler, Ricardo Esteban, Lanati, L., Orozco, Maria Marcela, Schijman, Alejandro Gabriel   +5 more
core   +1 more source

Chagas disease and immunosuppression [PDF]

Memórias do Instituto Oswaldo Cruz, 1999
Chagas disease, caused by a hemoflagellate,Trypanosoma cruzi, is a parasitic disease widelydistributed throughout Latin America. It is trans-mitted to man by hematophagous vectors (redu-viid bugs), blood transfusion and, more rarely, byoral route, laboratory accidents, and from motherto fetus.
openaire   +3 more sources

Cost‐Effectiveness of Applying Fluoride Varnish to Preschoolers in a Brazilian Scenario: An Economic Modelling Study

Community Dentistry and Oral Epidemiology, EarlyView.
ABSTRACT Background International economic evaluations have not found convincing evidence that the application of fluoride varnish (FV) in preschool children is a cost‐effective anti‐caries measure, and there is a lack of economic evaluations of FV in the Brazilian context.
Izabel Monteiro Dhyppolito, Rodolfo Castro, Ana Paula Pires dos Santos, Paulo Nadanovsky   +3 more
wiley   +1 more source

Perspectives on the Trypanosoma cruzi-host cell receptor interaction [PDF]

, 2009
Chagas disease is caused by the parasite Trypanosoma cruzi. The critical initial event is the interaction of the trypomastigote form of the parasite with host receptors. This review highlights recent observations concerning these interactions.
A Belley, A Buschiazzo, AC Frasch, AC Monteiro, AC Monteiro, AG Todorov, AJS Augustine, AK Vaidian, AL Leal, AM Celentano, AM Silber, AM Woolsey, Anthony W. Ashton, AP Lima, AW Ashton, AW Ashton, BA Burleigh, BA Burleigh, BA Burleigh, BK Kubata, C Claser, CA Buscaglia, CA Petersen, CW Turner, E Del Nery, E Ortega-Barria, F Leeb-Lundberg, F Marceau, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, F Villalta, Fabiana S. Machado, Fangxia Guan, Fernando Villalta, GS Hassan, HB Tanowitz, HB Tanowitz, HB Tanowitz, HB Tanowitz, Herbert B. Tanowitz, Huan Huang, IC Cuevas, IM Bastos, J Aliberti, J Scharfstein, J Scharfstein, JC Engel, JL Croxford, JM Di Noia, Julio Scharfstein, K Kabashima, KD Bhoola, Kevin M. Tyler, KJ Simmons, KM Tyler, L Sterin-Borda, LO Andrade, Louis M. Weiss, LX Liu, M de Melo-Jorge, M Einicker-Lamas, M Ming, MA Campos, MA Ouaissi, Maria F. Lima, MC Taylor, ME McGrath, MF Lima, MF Lima, MH Magdesian, MJ Alves, MN Meirelles, MV Chuenkova, MV Chuenkova, MV Chuenkova, MV Chuenkova, N Garg, N Garg, N Yoshida, P Grellier, PJ Pereira, PN Nde, R Agusti, R Giordano, R Manning-Cela, RA Skidgel, RL Cardoni, S Favoreto Jr, S Mukherjee, S Mukherjee, S Mukherjee, S Schenkman, S Vaena de Avalos, Sandra Alvarez, SB Petkova, SB Petkova, SG Andrade, Shankar Mukherjee, SM Factor, T Moody, VL Hideko Tatakihara, YY Kleshchenko   +108 more
core   +1 more source