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Most patients with chronic Chagas disease (CD) present the indeterminate form and are at risk to develop the cardiac form. However, the actual rate of progression to the cardiac form is still unknown.
Alejandro Marcel Hasslocher-Moreno+11 more
doaj +1 more source
Critical analysis of Chagas disease treatment in different countries [PDF]
Chagas disease; Treatment; BenznidazoleEnfermedad de Chagas; Tratamiento; BenznidazolMalaltia de Chagas; Tractament; BenznidazolAs a result of globalization and constant migratory flows, Chagas disease is now present in almost all continents.
Angheben, Andrea+5 more
core +2 more sources
Chagas’ disease is a protozoan infection caused by Trypanosoma cruzi and is mainly acquired by vectorial transmission in endemic areas, when infected excreta of Triatominae bugs are inoculated into the sting site or neighbouring mucous membranes of the victim.
Marin-Neto, José Antonio+2 more
openaire +6 more sources
Fundamental research on EV isolation, standardization and characterisation will bring about translational medical diagnostics and therapy. Abstract Extracellular vesicles (EVs) are a unique and heterogeneous class of lipid bilayer nanoparticles secreted by most cells.
Karina P. De Sousa+5 more
wiley +1 more source
Chagas disease in prehistory [PDF]
The classical hypothesis proposes that Chagas disease has been originated in the Andean region among prehistoric people when they started domesticating animals, changing to sedentary habits, and adopting agriculture. These changes in their way of life happened nearly 6,000 years ago.
Ferreira, Luiz F.+2 more
openaire +6 more sources
Diagnosis of Trypanosoma cruzi (T. cruzi) infection in the chronic phase of Chagas disease (CD) is performed by serologic testing. Conventional tests are currently used with very good results but require time, laboratory infrastructure, and expertise ...
Jacqueline Araújo Domingos Iturra+11 more
doaj +1 more source
Chagas' disease, caused by Trypanosoma cruzi, is an important cause of morbidity in many countries in Latin America. The important modes of transmission are by the bite of the reduviid bug and blood transfusion. The organism exists in three morphological forms: trypomastigotes, amastigotes, and epimastigotes.
H B, Tanowitz+5 more
openaire +2 more sources
Background Chagas disease is endemic in Latin America and, over the last few decades, due to population movements, the disease has spread to other continents. Early diagnosis and treatment are critical in terms of improving outcomes for those living with
María Romay-Barja+4 more
doaj +1 more source
Electrocardiogram in Chagas disease [PDF]
Since the initial descriptions of Chagas cardiomyopathy (ChCM), the electrocardiography has played a key role in patient evaluations. The diagnostic criterion of chronic ChCM is the presence of characteristic electrocardiographic (ECG) abnormalities in seropositive individuals, regardless of the presence of symptoms.
Brito, Bruno Oliveira de Figueiredo+1 more
openaire +6 more sources
Mortality among blood donors seropositive and seronegative for Chagas disease (1996-2000) in São Paulo, Brazil: A death certificate linkage study. [PDF]
Individuals in the indeterminate phase of Chagas disease are considered to have mortality rates similar to those of the overall population. This study compares mortality rates among blood donors seropositive for Chagas disease and negative controls in ...
Ligia Capuani+7 more
doaj +1 more source