Results 41 to 50 of about 101,506 (305)

Was Chagas disease responsible for Darwin’s illness? The overlooked eco-epidemiological context in Chile

Revista Chilena de Historia Natural, 2021
The source of Darwin’s illness has been a contentious issue in the literature for almost 70 years. Different causal factors have been invoked to account for his symptoms, including Chagas disease.
Carezza Botto-Mahan, Rodrigo Medel
doaj   +1 more source

Immune complexes in chronic Chagas disease patients are formed by exovesicles from Trypanosoma cruzi carrying the conserved MASP N-terminal region [PDF]

, 2017
The exovesicles (EVs) are involved in pathologic host-parasite immune associations and have been recently used as biomarkers for diagnosis of infectious diseases.
De Pablos, Luis Miguel, Díaz Lozano, Isabel María, Longhi, Silvia Andrea, Osuna, Antonio, Schijman, Alejandro Gabriel, Zago, María Paola   +5 more
core   +3 more sources

Pupillometry in Chagas disease [PDF]

Arquivos Brasileiros de Oftalmologia, 2018
We investigated parasympathetic innervation abnormalities of the iris sphincter and ciliary muscles in chronic Chagas disease by measuring pupillary diameter and intraocular pressure.A group of 80 patients with Chagas disease was compared with 76 healthy individuals without chagasic infection.
Diva Vargas, Cleudson Castro, Cleudson Castro   +2 more
openaire   +4 more sources

Effect of an exercise-based cardiac rehabilitation program on quality of life of patients with chronic Chagas cardiomyopathy: results from the PEACH randomized clinical trial

Scientific Reports
To investigate the effect of an exercise-based cardiac rehabilitation program on the quality of life (QoL) of patients with chronic Chagas cardiomyopathy (CCC).
Marcelo Carvalho Vieira, Fernanda de Souza Nogueira Sardinha Mendes, Paula Simplício da Silva, Gilberto Marcelo Sperandio da Silva, Flavia Mazzoli-Rocha, Andrea Silvestre de Sousa, Roberto Magalhães Saraiva, Marcelo Teixeira de Holanda, Daniel Arthur Barata Kasal, Henrique Silveira Costa, Juliana Pereira Borges, Michel Silva Reis, Luiz Fernando Rodrigues Junior, Alejandro Marcel Hasslocher-Moreno, Pedro Emmanuel Alvarenga Americano do Brasil, Mauro Felippe Felix Mediano   +15 more
doaj   +1 more source

Duration of COVID-19 symptoms in children: a longitudinal study in a Rio de Janeiro favela, Brazil

BMJ Open
Objectives COVID-19 in children is generally of short duration, but some may take longer to recover. This study investigated the time to symptom resolution following SARS-CoV-2 infection among children in a community setting on the outskirts of an urban ...
Patrícia Brasil, Raquel de Vasconcellos Carvalhaes de Oliveira, Leonardo Bastos, Marilia Carvalho, Fernanda Esthefane Garrides Oliveira, Heloísa Ferreira Pinto Santos, Luana Santana Damasceno, Luiza Sales Franco, Liege Maria Abreu de Carvalho, Trevon Louis Fuller, Lusiele Guaraldo   +10 more
doaj   +1 more source

B‐EPIC: A Transformer‐Based Language Model for Decoding B Cell Immunodominance Patterns

Advanced Science, EarlyView.
B‐Epic: Achieving high‐accuracy B cell epitope prediction through Transformer architecture. Comprehensive validation demonstrates B‐Epic's robust performance across diverse datasets. B‐Epic facilitates vaccine development for H. pylori and EBV, addressing critical public health challenges.
Jun‐Ze Liang, Youtao Wang, Cong Sun, Tao Liu, Zengfeng Wu, Lipeng Chen, Lina Chen, Penglin Li, Zhengkang Li, Cangui Zhang, Bingyun Lu, Ye Chen, Bing Gu, Qian Zhong, Xin Wei Wang, Mu‐Sheng Zeng, Jinping Liu   +16 more
wiley   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

CrAg screening strategy reduces definitive sequelae in people living with HIV

Discover Viruses
Background Screenning cryptococcal antigen (CrAg) of people living with HIV (PLHIV) reduces the morbidity and development of cryptococcal meningitis, but recent publications shows that it does not reduce mortality when comparable with a negative CrAg ...
Marcela de Faria Ferreira, Fabio Brito-Santos, Marcos de Abreu Almeida, Luciana Trilles, Marcia dos Santos Lazera   +4 more
doaj   +1 more source

Co‐cultivation and Medium Optimization: A Strategy for Discovering Fungal‐derived Protease Inhibitors

Chemistry &Biodiversity, EarlyView.
ABSTRACT The fungi Fusarium guttiforme and Phytophthora palmivora were cultivated in four different media (Potato Dextrose Agar, Czapek, rice, and ISP2) and co‐cultured to stimulate fungal interactions and enhance secondary metabolite production. Promising extracts were fractionated, yielding compounds such as the iron complex of fusaric acid (1 ...
Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Adriano Defini Andricopulo, Gisele Barbosa, Renata Krogh, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +7 more
wiley   +1 more source

Chagas disease reactivation in a heart transplant patient infected by domestic Trypanosoma cruzi discrete typing unit I (TcIDOM) [PDF]

, 2015
Background Trypanosoma cruzi, causative agent of Chagas disease, displays high intraspecific genetic diversity: six genetic lineages or discrete typing units (DTUs) are currently recognized, termed TcI through TcVI.
Bhattacharyya, T., Burleigh, B.A., Costales, J.A., Garcia-Perez, J., Kotton, C.N., Llewellyn, M.S., Messenger, L.A., Zurita-Leal, A.C.   +7 more
core   +2 more sources