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Abstract Chagas disease is the clinical condition triggered by infection with the protozoan Trypanosoma cruzi. The infection is transmitted by triatomine insects while blood feeding on a human host. Field studies predict that one third of an estimated 18 million T cruzi-infected humans in Latin America will die of Chagas disease.
A R L, Teixeira+4 more
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Autochthonous Chagas Disease in the United States: How Are People Getting Infected?
In the United States, Chagas disease is diagnosed in less than 1% of the estimated > 300,000 people who have the disease. However, the actual prevalence remains unknown, and these estimates may be wide of the mark (too high or too low).
Norman L. Beatty, S. Klotz
semanticscholar +1 more source
Chagas disease (CD) persists as one of the neglected tropical diseases (NTDs) with a particularly large impact in the Americas. The World Health Organization (WHO) recently proposed goals for CD elimination as a public health problem to be reached by ...
Collaborating Group on Chagas Disease Modelling
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Contemporary characteristics and outcomes in chagasic heart failure compared with other nonischemic and ischemic cardiomyopathy [PDF]
Background: Chagas’ disease is an important cause of cardiomyopathy in Latin America. We aimed to compare clinical characteristics and outcomes in patients with heart failure (HF) with reduced ejection fraction caused by Chagas’ disease, with other ...
Claudio R. Gimpelewicz+17 more
core +3 more sources
Animal models of Chagas disease and their translational value to drug development
Introduction American trypanosomiasis, better known as Chagas disease, is a global public health issue. Current treatments targeting the causative parasite, Trypanosoma cruzi, are limited to two old nitroheterocyclic compounds; new, safer drugs are ...
E. Chatelain, Ivan Scandale
semanticscholar +1 more source
Chagas disease is currently present in many non-endemic countries and remains a neglected tropical disease globally. A review of the literature identified significant gaps and scarcity of updated information from European countries, with most studies reporting data from Spain and Italy.
Marta Gonzalez-Sanz+5 more
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Cultural barriers to effective communication between Indigenous communities and health care providers in Northern Argentina: an anthropological contribution to Chagas disease prevention and control [PDF]
INTRODUCTION: Ninety percent of the aboriginal communities of Argentina are located in areas of endemic vectorial transmission of Chagas disease. Control activities in these communities have not been effective.
Braunstein, Jose Alberto+5 more
core +1 more source
Chagas Disease Infection Reactivation after Heart Transplant
Chagas disease, caused by a Trypanosona cruzi infection, is one of the main causes of heart failure in Latin America. It was originally a health problem endemic to South America, predominantly affecting residents of poor rural areas.
M. Moreira, J. Renan Cunha-Melo
semanticscholar +1 more source
Objective: The goal of this study was to examine the association between ECG repolarization parameters and mortality in Chagas disease (CD) patients living in the United States.
Jason Bradfield, MD+6 more
doaj +1 more source
American trypanosomiasis and Chagas disease: Sexual transmission
Objective: To contribute to the discussion on the research findings indicating the sexual transmission of American trypanosomiasis and Chagas disease in humans.
Clever Gomes+4 more
doaj +1 more source