Results 101 to 110 of about 1,093,565 (287)

Entanglement asymmetry in periodically driven quantum systems

open access: yesSciPost Physics
We study the dynamics of entanglement asymmetry in periodically driven quantum systems. Using a periodically driven XY chain as a model for a driven integrable quantum system, we provide semi-analytic results for the behavior of the dynamics of the ...
Tista Banerjee, Suchetan Das, Krishnendu Sengupta
doaj   +1 more source

Research on reliability of scraper chain drive system

open access: yesIOP Conference Series: Materials Science and Engineering, 2018
Qipeng Ma, Junxia Li
openaire   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Structure Optimization of Chain Plate of Double-pitch Silent Chain for Conveyor

open access: yesJixie chuandong, 2017
The chain plate structure of double pitch silent conveyor chain is the variation structural of internal and external composite engaged standard silent chain.
Tian Hui   +5 more
doaj  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

Research on Modification of Bending Machine Sprockets and Its Influence

open access: yesJixie chuandong
In view of the impact and fatigue failure caused by the chain transmission system of a bending machine, the dynamic characteristics of the chain drive and the modification of the sprocket are analyzed and studied.
Xia Zhongrui, Wang Huipeng, Ou Jianbin
doaj  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

汽车发动机正时链带阻尼装置的横向振动分析

open access: yesJixie chuandong, 2009
A model of transverse vibration of automotive engine timing chain with damper that was modeled as a single degree of freedom system which consists of a mass and a spring was developed from Multi-DOF system theory based on finite centralized mass ...
陈景昌   +3 more
doaj  

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