Results 101 to 110 of about 256,334 (280)

Optimization Design of Drive Mode of Coiled Tubing Injector Head

Shiyou jixie, 2017
At present, there are some defects in the actual use of coiled tubing injector head drive method. In order to address these defects and improve the performance of the injector head, focusing on the structural characteristics of the injector head and ...
Duan Wenyi, Liu Pingguo, Liu Fei, Ma Qing, Hao Jun, Hu Zhiqiang   +5 more
doaj  

AI-Driven Financial Analysis: Exploring ChatGPT’s Capabilities and Challenges

International Journal of Financial Studies
The transformative impact of AI technologies on the financial sector has been a topic of increasing interest. This study investigates ChatGPT’s applications in financial reasoning and analysis and evaluates ChatGPT-4o’s effectiveness and limitations in ...
Li Xian Liu, Zhiyue Sun, Kunpeng Xu, Chao Chen   +3 more
doaj   +1 more source

Identification of a Complex Drive Chain Based on Local Linear Model Tree

, 2013
This paper uses the local linear model tree (LOLIMOT) method for modeling the angular velocity of a complex nonlinear system called Gamma-log. The drive chain of the Gamma-log contains nonlinear parts such as an AC servo drive or a worm gear drive.
Kovács, Ernő, Füvesi, Viktor, Vörös, Csaba   +2 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Transient Vibrations During Acceleration and Braking of Bucket Elevator Chain

Applied Sciences
The paper deals with an analysis of transverse vibrations of a bucket elevator chain, arising during the acceleration and braking process of the drive sprocket.
Waldemar Łatas, Zygmunt Dziechciowski
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A Case Study on Performance Analysis of Chain Drive Conveyor System

This paper presents the design, analysis, and performance evaluation of a chain drive-based conveyor system used for industrial material handling applications. The study focuses on optimizing the transmission efficiency, load-carrying capacity, and durability of the drive components.
A. Gujar, P. Bamankar, A. Awasare
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The Main Advantages of E-Drive System Used for Precision Seeding

, 2012
In this paper were analysed the main advantages of using electric drive system for the distribution discs used in precision sowing machines.The main quality indexes (Toma, D., 1987) of the seeds placement in the soil were analysed using a sowing ...
DROCAȘ, Ioan, STĂNILĂ, Sorin, RANTA, Ovidiu, MUNTEAN, Mircea, MARIAN, Ovidiu, MOLNAR, Adrian   +5 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source