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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
N,N′-Bis(2-azaniumylbenzyl)ethane-1,2-diaminium tetrachloride
The title compound, C16H26N44+·4Cl−, is based on a fully protonated tetraamine. In the cation, both benzene rings are connected by an all-trans chain, and the rings are almost parallel, with an angle between the mean planes of 8.34&
Luis Ángel Garza Rodríguez +4 more
doaj +1 more source
Weak dimension of FP-injective modules over chain rings
It is proven that the weak dimension of each FP-injective module over a chain ring which is either Archimedean or not semicoherent is less or equal to ...
Couchot, Francois
core +3 more sources
Supramolecular Buffering by Ring–Chain Competition
Recently, we reported an organocatalytic system in which buffering of the molecular catalyst by supramolecular interactions results in a robust system displaying concentration-independent catalytic activity. Here, we demonstrate the design principles of the supramolecular buffering by ring-chain competition using a combined experimental and theoretical
Paffen, TFE +3 more
openaire +5 more sources
Linear Codes over Finite Chain Rings [PDF]
The aim of this paper is to develop a theory of linear codes over finite chain rings from a geometric viewpoint. Generalizing a well-known result for linear codes over fields, we prove that there exists a one-to-one correspondence between so-called fat linear codes over chain rings and multisets of points in projective Hjelmslev geometries, in the ...
Honold, Thomas, Landjev, Ivan
openaire +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
3β-Chlorocholest-5-en-7-one
The title compound, C27H43ClO, is a steroid derivative composed of a saturated carbon fused-ring framework with an alkyl side chain. The A and C rings have chair conformations and the B and D rings assume half-chair conformations.
Hoong-Kun Fun +4 more
doaj +1 more source
Tightness of slip-linked polymer chains [PDF]
We study the interplay between entropy and topological constraints for a polymer chain in which sliding rings (slip-links) enforce pair contacts between monomers. These slip-links divide a closed ring polymer into a number of sub-loops which can exchange
A. Ashkin +94 more
core +3 more sources
A representation theorem for Chain rings [PDF]
Though usually a left `chain ring' means any ring whose left ideals are totally ordered by inclusion, in this paper the authors understand by a chain ring any local ring with identity, both sided Artinian and principal ideal ring. The main purpose of this paper it to establish a representation theorem for such rings in terms of appropriate homomorphic ...
Alkhamees, Yousef +2 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

