Results 31 to 40 of about 2,018,011 (296)

SASLedger: A Secured, Accelerated Scalable Storage Solution for Distributed Ledger Systems

open access: yesFuture Internet, 2021
Blockchain technology provides a “tamper-proof distributed ledger” for its users. Typically, to ensure the integrity and immutability of the transaction data, each node in a blockchain network retains a full copy of the ledger; however, this ...
Haoli Sun   +4 more
doaj   +1 more source

Simulation of Sales Scenarios in Chain Store Marketing with a Futuristic Approach

open access: yesInternational Journal of Innovation in Marketing Elements, 2021
This paper examines the simulation method as one of the future prediction techniques. In this article, while examining the concepts related to futuristic studies, one of the powerful tools in this field is introduced.
Paria Samadi-Parviznejad
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye   +33 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Chain-store competition: customized vs. uniform pricing [PDF]

open access: yes, 2008
Retail chains essentially practice one of two broad strategies in setting prices across their stores. The more straightforward is to set a chain- or country- wide price.
Dobson, Paul, Waterson, Michael
core  

A Pharmacy Computer System [PDF]

open access: yesApplied Medical Informatics, 2009
Objective: Describing a model of evaluation seen from a customer’s point of view for the current needed pharmacy computer system. Data Sources: literature research, ATTOFARM, WINFARM P.N.S., NETFARM, Info World - PHARMACY MANAGER and HIPOCRATE FARMACIE ...
Claudia CIULCA-VLADAIA, Călin MUNTEAN
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A mathematical model for optimum single-commodity distribution in the network of chain stores: a case study of food industry [PDF]

open access: yesManagement Science Letters, 2011
Distribution refers to the steps taken to move and store a product from the suppliers to a customers in the supply chain and is a key driver of the overall profitability of a firm and overall supply chain.
Mohsen Cheshmberah   +3 more
doaj  

Optimization of supply chain: solving the «BullWhip Effect» for supplier orders

open access: yesТехнічна інженерія, 2023
This research pays special attention to the analysis of the Bullwhip Effect (BE) in supply chains and its impact on increasing the variability of orders compared to end-user demand.
D.V.
doaj   +1 more source

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