Results 121 to 130 of about 10,987,289 (344)

Entrepreneurial Policing? International Policing Challenges [PDF]

, 2013
International police assistance is a global growth industry. Democratic police reform has become a cornerstone of security sector reform within peacebuilding and capacity building programmes. The UK provides police for a wide range of missions across the
Ellison, Graham, Sinclair, Georgina
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Personalized T cell-mediated cancer immunotherapy: progress and challenges

, 2017
Michael T. Bethune, Alok V. Joglekar
openalex   +2 more sources

Special Issue From research to development to implementation: challenges in health informatics and health information management [PDF]

, 2008
Peter A. Bath
openalex   +1 more source

How autocrats cope with the corona challenge: Belarus vs. Russia

, 2022
Daniel J. Weiss
openalex   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Comprehensive review of One Health systems for emerging infectious disease detection and management

One Health
This systematic review investigates how One Health systems, integrated digital platforms combining human, animal, and environmental health data, are currently designed and implemented for infectious disease detection and management.
Aseel Basheer, Matthew Tran, Baseer Khan, Wolfgang Jentner, Aaron Wendelboe, Jason Vogel, Katrin Kuhn, Michael C. Wimberly, David Ebert   +8 more
doaj   +1 more source

Healthcare managerial challenges in rural and underserved areas: A Review [PDF]

Oloruntoba Babawarun, Chioma Anthonia Okolo, Jeremiah Olawumi Arowoogun, Adekunle Oyeyemi Adeniyi, Rawlings Chidi   +4 more
openalex   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source