Results 121 to 130 of about 2,657,595 (252)

Building a Rural, Coalition-Based Approach to Youth Substance Use Prevention: The Drug Free Dickson Coalition Model. [PDF]

J Public Health Manag Pract
Thompson KR.
europepmc   +1 more source

109 Catalyzing systems change for early childhood development: innovations for equity and impact

BMJ Paediatrics Open
James Radner, Jasmine Lam, Andrew Bollington, Sanjana Janardhanan, Michelle Cruickshank   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Coadministration of fluoride, trimetaphosphate, and quercetin reduces dentin erosive wear in vitro. [PDF]

Clin Oral Investig
Gomes IMP, Delbem ACB, Martins TP, da Silva IF, Ferraresso LFOT, Capalbo LC, Buzalaf MAR, Monteiro DR, Pessan JP.   +8 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Challenges in Providing End-of-Life Nursing Care: A Qualitative Content Analysis. [PDF]

Nurs Open
Taheri-Ezbarami Z, Jafaraghaee F, Sighlani AK, Mousavi SK.   +3 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Longitudinal national surveys reflect steady challenges for AIDS drug assistance programs, 2017-2024. [PDF]

Front Public Health
Rogers EQ, Killelea A, Horn T, Panagides R, Keim-Malpass J, Liu F, Steen A, McManus KA.   +7 more
europepmc   +1 more source

Editorial Page

The Person and the Challenges, 2020
The Person and The Challenges
doaj  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source