Results 111 to 120 of about 4,075,413 (333)
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Saggio sulla fortuna. Le casualità fortuite nelle traiettorie biografiche delle giovani milanesi
The topic of luck has recently attracted new interest in anthropological literature, focusing on its role in understanding economic cosmologies. Lucky chances stand out in comparative perspective as a crucial cultural theme in contemporary western ...
Edda Orlandi
doaj +2 more sources
Evrenin bir başlangıcının olup olmadığı ya da bu düzenin nereden geldiğigibi sorular, insanlığın en büyük merakıdır. Fakat 18. Yüzyılda sanayi devrimininürünü olan buhar makinelerinin çalışma prensiplerinin keşfiyle birlikte doğan termodinamikve ...
Fatih Özgökman
doaj
The "scenario approach" provides an intuitive method to address chance constrained problems arising in control design for uncertain systems. It addresses these problems by replacing the chance constraint with a finite number of sampled constraints ...
Goulart, Paul+4 more
core +1 more source
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
ARİSTOTELES VE FARABİ'NİN FELSEFESİNDE RASTLANTININ YERİ
İsmail ERDOĞAN, ARİSTOTELES VE FARABİ'NİN FELSEFESİNDE RASTLANTININ ...
İsmail Erdoğan
doaj
On Functions of Sequences of Independent Chance Vectors with Applications to the Problem of the "Random Walk" in $k$ Dimensions [PDF]
David Blackwell, M. A. Girshick
openalex +1 more source
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source