Results 41 to 50 of about 822,135 (241)

STRATEGIC MANAGEMENT OF THE ECONOMIC SUSTAINABILITY OF A COMPANY IN THE PARADIGM OF FUZZY LOGIC

open access: yesСтратегические решения и риск-менеджмент, 2023
The theory of economic resilience is actively developing in Russian and foreign scientific studies. Most of them lack a comprehensive approach to the issue of resilience, the ability to assess the behaviour of economic systems under conditions of ...
Yu. A. Malyukov   +2 more
doaj   +1 more source

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa   +3 more
wiley   +1 more source

Gaio Mario e le Minturnenses paludes fra storia e topos di commutatio fortunae (I sec. a.C. – V sec. d.C.)

open access: yesPallas, 2022
Gaius Marius’ flight was the symbol of luck changing within Greco-Roman culture. This paper analyzes an extrapolated account of the famous escape, comparing the different versions of this tale: Marius in the Minturnae marshes.
Pierfrancesco Musacchio
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Intorno ad alcuni modi del caso in Darwin a partire dal Doktorarbeit di Wilhelm Windelband [PDF]

open access: yesS&F_scienzaefilosofia.it, 2022
On some models of chance in Darwin starting from Wilhelm Windelband’s Doktorarbeit The incidence of the notion of chance in the evolutionary mechanism that Charles Darwin envisages in On the origin of species (1859) is one of the basic reasons why the ...
MASSIMILLA, EDOARDO
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Chance as a subversive element in the 1960s philosophical and aesthetic discourse [PDF]

open access: yesSlovenska Literatura, 2011
The author uses chosen texts (philosophical essays) and films of the 1960s new wave as examples to demonstrate the function of chance serving as a subversive element in the philosophical and aesthetic discourse of the time.
Pavel Matejovič
doaj  

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