Results 111 to 120 of about 1,915,229 (296)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Exploratory research on big data application of analysis and forecasting in economics of tax
大数据, 2017 Based on the current forecasting theory and practice in the economics of tax,big data applications give chance for the improvement and development of theory and practice.The main progress and characters in this field were summarized.The main progress and
Bofeng XIE
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
The problem of hell and the second chance theory in Anglo-American philoso-phy of religion
Idei, 2017 Problem of hell is a philosophical problem related to theological doctrine of eternal pun-ishment. It is a variation of the problem of evil. With a few exceptions, the traditional concept of hell has prevailed in Christian thought since the time of early
Valery Kuzev
doaj
A Game-Theoretic History of the Cuban Missile Crisis
Economies, 2014 This study surveys and evaluates previous attempts to use game theory to explain the strategic dynamic of the Cuban missile crisis, including, but not limited to, explanations developed in the style of Thomas Schelling, Nigel Howard and Steven Brams. All
Frank C. Zagare
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Considerations on probability: from games of chance to modern science
Statistica, 2015 The article sets out a number of considerations on the distinction between variability and uncertainty over the centuries. Games of chance have always been useful random experiments which through combinatorial calculation have opened the way to ...
Paola Monari
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Solution of Einstein’s Causality Problem: The AHK Theorem [PDF]
'Chance' is defined as an event on the time scale withour any cause before it appears. That means, that cause and effect is identical. This is the only way to integrate chance into a consistent theory of causality.
Kaiser, Peter M.
core
Probability and chance in the theory of statistics [PDF]
Proceedings of the Royal Society of London. Series A, Containing Papers of a Mathematical and Physical Character, 1933 1. The distinction between probability and chance .—Probability is of fundamental importance in statistical theory, which indeed we may regard merely as part of the mathematical theory of probability; yet statisticians still differ widely in opinion, among themselves as well as with others, on what it means and on ...
openaire +1 more source