Results 101 to 110 of about 9,294,041 (227)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

PETROLOGICAL, CHEMICAL, AND CHRONOLOGICAL STUDY OF BRECCIAS IN THE CHANG’E-5 SOIL

open access: yes
We carried out a petrological, mineralogical, and geochemical study of fragmental and regolith breccia clasts separated from two Chang’e-5 soil samples, CE5C0000YJYX03501GP and CE5C0400, which provide an opportunity to investigate the compositional ...
Snape, Joshua F.; id_orcid   +2 more
core   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A Horizon Tracking Algorithm for Chang’E-4 Lunar Surface Penetrating Radar Based on Dynamic Search Center

open access: yesLeida xuebao
The Moon’s shallow subsurface structure provides crucial insights into its geological evolution, material composition, and space weathering processes. With the acquisition of extensive radar datasets from recent lunar exploration programs, such as the ...
Yuxiao ZHI   +7 more
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Chang’e and the Moon a Contemporary Chamber Opera [PDF]

open access: yes, 2017
The full-length chamber opera Chang’E and the Moon, inspired by elements of Chinese literary, philosophical and musical culture, is a retelling of the myth surrounding the Chinese Goddess of the Moon and the Mid-Autumn Festival.
Fox, Rowen John
core  

Chang'E-4 rover spectra revealing micro-scale surface thermophysical properties of the Moon

open access: yes, 2020
Dataset of the article 'Chang’E-4 rover spectra revealing micro-scale surface thermophysical properties of the ...
Yunzhao Wu
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Software Design for Centralized Monitor of Chang’E-1 Operational Simulator

open access: yes, 2011
Operational simulator is a simulated training system used in a flight control center to train and improve mission operators’ ability to control and track spacecrafts, constructing a realistic mission-like circumstance for the system drilling.
Yong Ping Ma   +3 more
core   +1 more source

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