Results 111 to 120 of about 559 (225)

ERRATUM: Diverse rock types detected in the lunar South Pole–Aitken Basin by the Chang’E-4 lunar mission [PDF]

, 2020
Jun Huang, Zhiyong Xiao, Long Xiao, Briony Horgan, Xiaoyi Hu, Paul Lucey, Xiao Xiao, Siyuan Zhao, Yuqi Qian, Hao Zhang, Chunlai Li, Rui Xu, Zhiping He, Jianfeng Yang, Bin Xue, Qi He, Jie Zhong, Hongyu Lin, Changning Huang, Jianfeng Xie   +19 more
openalex   +1 more source

Yutu-2 radar observation of the lunar regolith heterogeneity at the Chang’E-4 landing site [PDF]

, 2022
Chunyu Ding, Siting Xiong, Jing Li, Yan Su, Shaopeng Huang   +4 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The First Laser Retroreflector on the Lunar Far Side Onboard China’s Chang’e-6 Lander

Space: Science & Technology
The Chang’e-6 (CE-6) lander-ascender combination softly touched down at the designated landing site in the Apollo basin within the South Pole–Aitken (SPA) basin on 2024 June 2.
Yexin Wang, Simone Dell’Agnello, Kaichang Di, Marco Muccino, Hongqian Cao, Luca Porcelli, Xiangjin Deng, Lorenzo Salvatori, Jinsong Ping, Mattia Tibuzzi, Yuqiang Li, Luciana Filomena, Zhizhong Kang, Michele Montanari, Zhanfeng Meng, Lorenza Mauro, Bin Xie, Mauro Maiello   +17 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

HIGH PRECISION DTM AND DOM GENERATING USING MULTI-SOURCE ORBITAL DATA ON CHANG’E-4 LANDING SITE [PDF]

, 2019
B. Liu, Shengli Niu, Xiaozhou Xin, Mengna Jia, Kaichang Di, Zaihua Liu, M. Peng, Zongyu Yue   +7 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Lunar dust: Formation, microphysics, and transport

Physical Review Research
Lunar dust—the submillimeter fraction of the regolith—controls the optical, thermophysical, electrical, mechanical, and environmental behavior of the Moon's surface.
Slava G. Turyshev
doaj   +1 more source