Results 91 to 100 of about 469 (186)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Non-KREEP origin for Chang'e-5 basalts in the Procellarum KREEP Terrane. [PDF]

Nature, 2021
Tian HC, Wang H, Chen Y, Yang W, Zhou Q, Zhang C, Lin HL, Huang C, Wu ST, Jia LH, Xu L, Zhang D, Li XG, Chang R, Yang YH, Xie LW, Zhang DP, Zhang GL, Yang SH, Wu FY.   +19 more
europepmc   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Two-billion-year-old volcanism on the Moon from Chang'e-5 basalts. [PDF]

Nature, 2021
Li QL, Zhou Q, Liu Y, Xiao Z, Lin Y, Li JH, Ma HX, Tang GQ, Guo S, Tang X, Yuan JY, Li J, Wu FY, Ouyang Z, Li C, Li XH.   +15 more
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Constraining the formation and transport of lunar impact glasses using the ages and chemical compositions of Chang'e-5 glass beads. [PDF]

Sci Adv, 2022
Long T, Qian Y, Norman MD, Miljkovic K, Crow C, Head JW, Che X, Tartèse R, Zellner N, Yu X, Xie S, Whitehouse M, Joy KH, Neal CR, Snape JF, Zhou G, Liu S, Yang C, Yang Z, Wang C, Xiao L, Liu D, Nemchin A.   +22 more
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Distribution and Abundance of Solar Wind‐Derived Water in Chang'E‐5 Core Samples and Its Implications

Geophysical Research Letters
Knowledge regarding the abundance and distribution of solar wind (SW)‐sourced water (OH/H2O) on the Moon in the shallow subsurface remains limited. Here, we report the NanoSIMS measurements of H abundances and D/H ratios on soil grains from three deepest
Heng‐Ci Tian, Jialong Hao, Yangting Lin, Yuchen Xu, Ziliang Jin, Chi Zhang, Wei Yang, Sen Hu, Ruiying Li, Zongyu Yue, Qiuli Li, Yong Wei, Xianhua Li, Fuyuan Wu   +13 more
doaj   +1 more source

Bi-directional reflectance, polarization, and spectroscopic measurements of the Chang'e-5 regolith sample

Astronomy & Astrophysics
Context. Optical measurement is a powerful tool for retrieving the regolith physical properties of the lunar surface. Aims. It has been a long-standing question in planetary remote sensing whether laboratory measurements are consistent with remote ...
Jiang Te, Zhang Hao, Ma Pei, Zhuang Yan, Hu Xiaoyi, Zhu Meng-Hua, Shkuratov Yuriy G., Lucey Paul G., Li Chunlai, Zhou Qin, Zuo Wei, Britt Daniel   +11 more
doaj   +1 more source

A dry lunar mantle reservoir for young mare basalts of Chang'e-5. [PDF]

Nature, 2021
Hu S, He H, Ji J, Lin Y, Hui H, Anand M, Tartèse R, Yan Y, Hao J, Li R, Gu L, Guo Q, He H, Ouyang Z.   +13 more
europepmc   +1 more source