Results 91 to 100 of about 8,419,467 (214)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Original data for the manuscript entitled "Diverse space-weathered rims on ilmenite: constraining the exposure history depth profiles of Chang’e-5 lunar soils"

open access: yes, 2023
The original EELS, and TEM data for the manuscript entitled "Diverse Space-Weathered Rims on Ilmenite Grains: Constraining the Exposure History Depth Profiles of Chang’e-5 Lunar Soil".THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE ...
Guo, Z (via Mendeley Data)
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Original TEM and EELS data for “Source of lunar magnetic anomalies: Magnetic vortex state of α-Fe in Chang’E-5 soil

open access: yes, 2023
Original TEM and EELS data for “Source of lunar magnetic anomalies: Magnetic vortex state of α-Fe in Chang’E-5 soil”THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Liu, P (via Mendeley Data)
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Data for: Digital elevation model, illumination and communication conditions at landing region for the Chang’E-5 mission based on LOLA data

open access: yes, 2019
Digital elevation model,the models of illumination and communication conditions at landing region for the Chang’E-5 mission based on LOLA ...
Li, F
core   +2 more sources

Unusual corona texture around olivine in Chang’e-5 regolith formed by impact process on the Moon

open access: yesEarth, Planets and Space
Impact-cratering is a ubiquitous geologic process on the Moon. The impact-induced mineralogical micro-structures in lunar sample can provide information about their formation conditions on the Moon.
Haojin Hu   +6 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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