Results 111 to 120 of about 2,624,164 (273)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Bootstrap for change point detection
, 2017 In Change point detection task Likelihood Ratio Test (LRT) is sequentially applied in a sliding window procedure. Its high values indicate changes of parametric distribution in the data sequence. Correspondingly LRT values require predefined bound for their maximum.
Buzun, Nazar, Avanesov, Valeriy
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Change Point Detection for Diversely Distributed Stochastic Processes Using a Probabilistic Method
Inventions, 2019 Unpredicted deviations in time series data are called change points. These unexpected changes indicate transitions between states. Change point detection is a valuable technique in modeling to estimate unanticipated property changes underlying time ...
Muhammad Rizwan Khan, Biswajit Sarkar
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
High-dimensional change-point detection with sparse alternatives
, 2013 We consider the problem of detecting a change in mean in a sequence of Gaussian vectors. Under the alternative hypothesis, the change occurs only in some subset of the components of the vector.
Enikeeva, Farida, Harchaoui, Zaid
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Bayesian multiple changing-points detection
AIMS MathematicsThis study investigated the application of Bayesian multiple change-point detection techniques in the context of piecewise polynomial signals. Given the limited number of existing methodologies for identifying change-points in such signals, we proposed an objective Bayesian change-point detection approach that accommodated heterogeneous error ...
Sang Gil Kang, Woo Dong Lee, Yongku Kim
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Nonparametric change point detection in regression
, 2019 This paper considers the prominent problem of change-point detection in regression. The study suggests a novel testing procedure featuring a fully data-driven calibration scheme. The method is essentially a black box, requiring no tuning from the practitioner. The approach is investigated from both theoretical and practical points of view.
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Near Real-Time Anomaly Detection and Localization in Tier-2 ISP Networks
IEEE AccessNear real-time anomaly detection and localization are critical requirements for operational Internet Service Provider (ISP) networks, where short-lived performance degradations can significantly affect service quality. However, widely deployed monitoring
Handoko Baguswasito +1 more
doaj +1 more source