Results 161 to 170 of about 9,693,328 (298)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Transforming climate change and health practice: a follow-up survey of participants in a global online professional education programme. [PDF]

BMJ Public Health
Rachman A, Sun Y, Babcock-Dunning L, Timm K, Dubrow R, Carrión D.   +5 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Will Urban Planning Change with the Climate?

, 2010
How urban planning and land use may accommodate the impacts of climate change.not peer reviewedSubmitted by Anthony Larson (alarson6@illinois.edu) on 2010-06-15T20:29:59Z No.
Boyer, Robert, Deal, Brian Michael
core  

Climate Change and Sustainable Healthcare: Knowledge, Attitudes, and Educational Role of Healthcare Workers. [PDF]

Healthcare (Basel)
Sansone V, Paduano G, Liguori F, Gallè F, Pelullo CP.   +4 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A Journey of Growth: Advancing the Future of [PDF]

운동과학
Ji-Seok Kim, Jinkyung Cho, Hyuntae Park
doaj   +1 more source

Evolutionary Footprint: A Systemic Indicator in Evolution, Ecology and Conservation. [PDF]

Evol Appl
Genissel T, Robert A, Lecomte J, Sarrazin F.   +3 more
europepmc   +1 more source

Change! Change! Change!

College & Research Libraries, 1974
openaire   +2 more sources

Change, Change, Change: Heeding the Call

Molecular Biology of the Cell, 2010
openaire   +3 more sources