Results 171 to 180 of about 35,791,731 (317)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Renewal of challenging behavior in an intensive outpatient clinic: Replication and extension to task changes. [PDF]
Aggarwal I +6 more
europepmc +1 more source
Change, Change, Change: Heeding the Call
openaire +3 more sources
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
In-Session Predictors of Treatment Outcome for Intimate Partner Violence: An Examination of Fathers for Change and Treatment as Usual. [PDF]
Shayani DR +3 more
europepmc +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Social media analysis reflects the negative sentiments experienced at both time changes with somewhat more depressive impact in early fall. [PDF]
Ellman B +3 more
europepmc +1 more source

