Results 51 to 60 of about 9,693,328 (298)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Climate Change and Water

open access: yes, 2008
Observational records and climate projections provide abundant evidence that freshwater resources are vulnerable and have the potential to be strongly impacted by climate change, with wide-ranging consequences for human societies ...
Kundzewicz, Zbigniew   +2 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

U.S. National Climate Change Assessment

open access: yes, 2014
The report summarizes the science of climate change and the impacts of climate change in the United States, now and in the ...
Yohe, Gary W.   +3 more
core  

International Migration of Qualified Human Resources in Social Assistance. Value Dimensions and Professional Dilemmas [PDF]

open access: yesAnnals of Philosophy, Social and Human Disciplines, 2017
International migration of work force is presently a high amplitude phenomenon. Romanian people have emigrated for work around the world, being engaged both in the physically hardest jobs and in activities that require completion of specialized courses ...
Viorica-Cristina CORMOŞ
doaj  

From the individual to the collective: Repositioning assessment as a social practice

open access: yesSOTL in the South, 2023
Although assessment theorists have long argued that assessment is a contextually located social practice, objectivist and psychometric discourses about assessment persist.
Cheng-Wen Huang   +2 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Enhancing climate change communication: Strategies for profiling and targeting Australian interpretive communities

open access: yes, 2013
This research aimed to provide practical information about how to design communications on climate change adaptation and target these to the Australian population.
Reser, Joseph   +12 more
core  

The Caribbean Community Climate Change Centre Strategic & Implementation Plan 2021-2025 : empowering people to act on climate change [PDF]

open access: yes, 2021
The Caribbean Community Climate Change Centre’s (CCCCC) Strategic and Implementation Plan 2021-2025, Empowering People to Act on Climate Change1 provides direction and focuses the efforts of the CCCCC on how to contribute to a Caribbean region that is ...
Caribbean Community Climate Change Centre
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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