Results 191 to 200 of about 6,834,000 (312)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Correction: A Global Industry Survey on Post-Approval Change Management and Use of Reliance. [PDF]

Ther Innov Regul Sci
Deavin A, Hossain A, Colmagne-Poulard I, Wong KC, Perea-Vélez M, Cappellini S, Ausborn S, Meillerais S, Bourguignon C.   +8 more
europepmc   +1 more source

Is Gaining Affective Commitment the Missing Strategy for Successful Change Management in Healthcare? [PDF]

J Healthc Leadersh, 2022
Harrison R, Chauhan A, Minbashian A, McMullan R, Schwarz G.   +4 more
europepmc   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

Change management - digitalisation of labor room: A mixed-methods study to assess the level of acceptance of 'Arc Partograph' application to go paperless in labor rooms. [PDF]

Eur J Obstet Gynecol Reprod Biol X
Narayan G, Patankar A, Narayan D, Suvvari TK, Chauhan A.   +4 more
europepmc   +1 more source

Teaching and fostering change management in medical education. [PDF]

Can Med Educ J, 2022
Li H, Do V, Rizzuti F.
europepmc   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Creating a Practical Transformational Change Management Model for Novel Artificial Intelligence-Enabled Technology Implementation in the Operating Room. [PDF]

Mayo Clin Proc Innov Qual Outcomes, 2022
Smith TG, Norasi H, Herbst KM, Kendrick ML, Curry TB, Grantcharov TP, Palter VN, Hallbeck MS, Cleary SP.   +8 more
europepmc   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Adoption of Closed-System Drug Transfer Devices: Effectiveness in Reducing Occupational Exposure to Hazardous Drugs and the Change Management Process. [PDF]

Can J Hosp Pharm
Hon CY, Ellis J, En Chiang TI, Jeronimo M, Ciconte R, Ménard AD.   +5 more
europepmc   +1 more source